Severe Sepsis/Septic Shock on Admission to the General Surgical ICU

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Severe sepsis/septic shock are serious complications of infection with high morbidity and mortality. Recent information showed that early and aggressive resuscitation may help improving survival and outcome especially the resuscitation within the first 3 hours. In surgical patients, either severe sepsis/septic shock bought them to the operating room or this sepsis might be found after surgery resulting in higher morbidity and mortality. Not only knowledge management, others possible risk factors should also be identified and corrected for outcome improving. This prospective observational study will be done in 800 adult surgical patients admitting to the general surgical intensive care unit. Incidence of severe sepsis/septic shock on admission along with risk factors associated with poor outcomes \[organ failure (AKI, ALI, PMI, liver failure, stroke), prolonged ICU length of, stay, ICU death\] will be recorded especially effect of amount and type of fluid replacement in the first 6 hours, 24, 48 and 72 hours after diagnosis. Outcome as major organ failure, ICU length of stay, ICU, 28 and 90 days mortality will also be study.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Maximum Age: 90
Healthy Volunteers: f
View:

• Adult (\> 18 years) surgical patient admitting to the general surgical ICU

• Consent to this study

Locations
Other Locations
Thailand
ICU Siamitra and ICU salad-Sumang, Deaprtment of Anesthesiology, Siriraj Hospital, Faculty of Medicine, Mahidol UNiversity, Bangkok, Thailand
RECRUITING
Bangkoknoi
Contact Information
Primary
Suneerat Kongsayreepong, MD
suneerat.kon@mahidol.ac.th
(661) 8427419
Backup
Onuma Chaiwat, MD
onuma27@hotmail.com
(664)-3882104
Time Frame
Start Date: 2011-06
Estimated Completion Date: 2024-06
Participants
Target number of participants: 800
Treatments
severe sepsis
severe sepsis/septic shock, organ failure, ICU death
Related Therapeutic Areas
Sponsors
Leads: Mahidol University

This content was sourced from clinicaltrials.gov