Probing Mechanisms of Procedural Memory Transformation with Cross-frequency Transcranial Alternating Current Stimulation (cf-tACS) As an Avenue to Sculpt Sensorimotor Behavior

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Sometimes, it is necessary to re-learn a previously learned movement behavior, for example, a bad posture during the golf drive or while playing the piano. Unlearning or relearning an intensively trained behavior is particularly important if the behavior is hampering recovery, for example, in chronic pain or after a stroke. With this pilot study, the brain mechanisms that control the change of pre-existing stable memories of a motor skill will be tested with electroencephalography (EEG). Non-invasive brain stimulation will be used to modulate these brain mechanisms and test if it is possible to change the pre-existing motor memory and the learning of a new motor skill.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Age 18 years or older (2/3 of the final sample will be ≥60years of age)

• No previous stroke, brain tumor, neurodegenerative disease, or trauma to the head

• Ability to give consent for study participation

• who have access to a personal computer with internet

Locations
United States
South Carolina
Medical University of South Carolina
RECRUITING
Charleston
Contact Information
Primary
Kirstin-Friederike Heise, PhD
heisek@musc.edu
(843)792-
Time Frame
Start Date: 2023-07-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 30
Treatments
Experimental: Active non-invasive brain stimulation during behavioral memory interference
Non-invasive brain stimulation with transcranial alternating current stimulation will be applied during a memory interference intervention.
Sham_comparator: Sham stimulation during behavioral memory interference
Inactive (sham) stimulation will be applied during a memory interference intervention.
Related Therapeutic Areas
Sponsors
Leads: Medical University of South Carolina

This content was sourced from clinicaltrials.gov