Perioperative Risk and Clinical Efficacy Study of Cervical Artery Stenosis Patients Through the Integration of Multimodal Imaging and Computational Fluid Dynamics

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

Ischemic stroke affects 2.5 to 3 million people annually in China, ranking as the leading cause of death and disability. Cervical artery stenosis is a significant contributor to this problem, with about 50% of patients experiencing cognitive impairment due to reduced cerebral blood flow. Two main surgical approaches, carotid endarterectomy (CEA) and carotid artery stenting (CAS), are used to treat severe cervical artery stenosis, but their effects on various factors remain unclear. This project collects multimodal imaging data, including CT perfusion and angiography, to create 3D models of cervical artery stenosis. Computational fluid dynamics and AI analysis are used to assess hemodynamics. By monitoring blood flow, oxygen levels, and evaluating postoperative outcomes, the goal is to tailor surgical approaches for better patient outcomes and improved quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• 1\) Clinical diagnosis of carotid stenosis.

Locations
Other Locations
China
Sichuan Provincial People's Hospital
RECRUITING
Chengdu
Contact Information
Primary
Lei Guo, Master
guoleii2021@hotmail.com
+86 15760551392
Backup
Li Xiong, Master
lcl1206778081@163.com
028-87393332
Time Frame
Start Date: 2023-06-01
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 40
Treatments
CEA group
The patient with carotid stenosis underwent CEA surgery.
CAS group
The patient with carotid stenosis underwent CAS treatment.
Related Therapeutic Areas
Sponsors
Leads: Sichuan Provincial People's Hospital

This content was sourced from clinicaltrials.gov