Facilitating Neuroplastic Changes of Acute Stroke Survivors With Severe Hemiplegia
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-stroke including patients who are paralyzed with no motor output. The early acute stroke rehabilitation device will be evaluated in this clinical trial.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 85
Healthy Volunteers: f
View:
• Acute first time unilateral hemispheric stroke (hemorrhagic or ischemic stroke, 24 hours after admission to 1 month post-stroke at the start of the proposed treatment)
• Hemiplegia or hemiparesis
• 0≤Manual Muscle Testing (MMT)\<=2
• Age 30-85
• Ankle impairments including stiff calf muscles and/or inadequate dorsiflexion
Locations
United States
Maryland
UMROI
RECRUITING
Baltimore
University of Maryland Baltimore
RECRUITING
Baltimore
Contact Information
Primary
Soh-Hyun Hur
SoHur@som.umaryland.edu
410 706-8625
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2028-08-31
Participants
Target number of participants: 68
Treatments
Experimental: Study group - Wearable ankle robot rehab
Wearable rehab robot with motor relearning with real-time feedback, passive stretching under intelligent control; Active movement training with robotic assistance
Active_comparator: Control group - Limited wearable ankle robot rehab
The same wearable robot used by the study group will be used for the control group but in a limited way: no motor relearning training under real-time feedback; passive movement in the joint middle range of motion instead of passive stretching; active movement training with no robotic assistance
Related Therapeutic Areas
Sponsors
Collaborators: The University of Texas Health Science Center, Houston
Leads: University of Maryland, Baltimore