Arterial Compliance as a Predictor of Clinical Outcomes With Intra-aortic Balloon Counterpulsation: A Prospective Observational Pilot Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock (CS). The investigators aim to compare clinical outcomes in CS patients requiring IABC with normal compliance versus low compliance. The study will enroll patients undergoing IABC that are clinically indicated. Baseline hemodynamic measurements will be obtained and then patients would be stratified based on their compliance. Post IABC, serial hemodynamic measurements will be obtained and compared between groups. Patients will continue to be followed longitudinally until the IABC has been discontinued for any reason. The proposed study will yield results that will aid in developing a larger clinical trial and ultimately assist clinicians in determining if IABC is appropriate therapy for patients in cardiogenic shock.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥18 years old

• Cardiogenic shock

• Undergoing Intra-aortic Balloon Counterpulsation (IABC) as part of clinical care

• Able to provide consent or have power of attorney or next of kin provide consent

Locations
United States
Pennsylvania
Thomas Jefferson University Hospital
RECRUITING
Philadelphia
Contact Information
Primary
Elizabeth R Westburg, MS
elizabeth.westburg@jefferson.edu
215-955-2050
Backup
Matthew S Delfiner, DO, MS
215-955-2050
Time Frame
Start Date: 2026-01-27
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 20
Related Therapeutic Areas
Sponsors
Leads: Thomas Jefferson University

This content was sourced from clinicaltrials.gov