Identifying Brain Regions Critical for Human Motor Learning Through Anatomic-functional Correlations of Deficits in Acute Stroke: Integrated Robotic and Voxel-based Lesion Symptom Mapping Approach
This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to identify the neural substrates underlying this inter-limb transfer. To achieve this, healthy individuals, acute and chronic stroke patients will perform proximal and distal MSkL tasks using serious games implemented on robotic devices. This will be complemented by behavioural assessments and multimodal MRI.
• First acute ischemic or hemorrhagic stroke
• Between the 2nd and 21st day post-stroke
• Age: 40-90 years
• Ability to complete the 3 consecutive sessions
• 40-90 years
• availability to complete three consecutive sessions.
• single stroke confirmed by brain imaging
• time since stroke onset \>6 months
• age between 40-90 years
• availability to complete three consecutive sessions.