Choice of the Optimal Method for Treatment of Acute Thrombophlebitis of the Varicose Great Saphenous Vein: Comparison of Endovenous Laser Ablation and Conservative Approach
Who is this study for? Patients with Endovenous Laser Ablation
Status: Completed
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
Рrospective single-centre randomized open-label study for comparison three modes of treatment for thrombosis of varicose great saphena vein - standard medical with fondaparinux sodium for 45 days, endovenous laser ablation close to the saphenofemoral junction with a 7-day course of anticoagulation and endovenous laser ablation close to the saphenofemoral junction without the use of anticoagulants.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age 18 years or more
• Acute thrombosis of varicose great saphenous vein and/or its major branches more than 5 cm from the saphenofemoral junction
• Signed informed consent
Locations
Other Locations
Russian Federation
National Medical Research Center for Therapy and Preventive Medicinel
Moscow
Time Frame
Start Date: 2021-08-16
Completion Date: 2023-12-01
Participants
Target number of participants: 105
Treatments
Active_comparator: Endovenous laser ablation without anticoagulants
Endovenous laser ablation without using of any anticoagulant
Active_comparator: Endovenous laser ablation with short-term anticoagulant
Endovenous laser ablation and subsequent 7 days of subcutaneous fondaparinux sodium
Active_comparator: Medical treatment
45 days of subcutaneous fondaparinux sodium
Authors
Konstantin A Kaperiz, Igor S Yavelov
Related Therapeutic Areas
Sponsors
Leads: National Medical Research Center for Therapy and Preventive Medicine