Probing the Efficacy of V5/MT Stimulation on Reading and Reading-related Measures in Children and Adolescents With Developmental Dyslexia

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation (tDCS) over left hemispheric direct Lateral Geniculate Nucleus (LGN)-V5/MT pathway, cerebral areas usually disrupted in individuals with DD. The investigators hypothesized that active tDCS over V5/MT will boost reading skills in children and adolescents with DD. On the contrary, sham (placebo condition) tDCS over V5/MT or active (control condition) tDCS over V1 will not have significant effect in improving reading skills. Further, both active and sham tDCS will be safe and well tolerated.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 13
Healthy Volunteers: t
View:

• Italian speakers right-handed children and adolescents with dyslexia (DSM-5, APA 2013);

• Word/nonword/text reading accuracy and/or speed at least 2 Standard Deviations below the mean for school-age;

• nv IQ ≥ 85;

• normal hearing and normal or corrected-to-normal vision.

Locations
Other Locations
Italy
Bambino Gesù Hospital and Research Institute
RECRUITING
Roma
Contact Information
Primary
Deny Menghini
deny.menghini@opbg.net
06.6859.2875
Backup
Giulia Lazzaro
giulia.lazzaro@opbg.net
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2026-08-31
Participants
Target number of participants: 36
Treatments
Experimental: HD-tDCS V5/MT, HD-tDCS V1, Sham
1. Active HD-tDCS over V5/MT~2. Active HD-tDCS over V1~3. Sham HD-tDCS over V5/MT or V1
Experimental: HD-tDCS V5/MT, Sham, HD-tDCS V1
1. Active HD-tDCS over V5/MT~2. Sham HD-tDCS over V5/MT or V1~3. Active HD-tDCS over V1
Experimental: HD-tDCS V1, HD-tDCS V5/MT, Sham
1. Active HD-tDCS over V1~2. Active HD-tDCS over V5/MT~3. Sham HD-tDCS over V5/MT or V1
Experimental: HD-tDCS V1, Sham, HD-tDCS V5/MT
1. Active HD-tDCS over V1~2. Sham HD-tDCS over V5/MT or V1~3. Active HD-tDCS over V5/MT
Experimental: Sham, HD-tDCS V5/MT, HD-tDCS V1
1. Sham HD-tDCS over V5/MT or V1~2. Active HD-tDCS over V5/MT~3. Active HD-tDCS over V1
Experimental: Sham, HD-tDCS V1, HD-tDCS V5/MT
1. Sham HD-tDCS over V5/MT or V1~2. Active HD-tDCS over V1~3. Active HD-tDCS over V5/MT
Related Therapeutic Areas
Sponsors
Leads: Bambino Gesù Hospital and Research Institute

This content was sourced from clinicaltrials.gov