Summary: In this study, researchers compared the outcomes of hypofractionated radiotherapy versus conventional radiotherapy for the treatment of diffuse intrinsic pontine glioma.
Summary: This study characterized children with pediatric high-grade glioma (pHGG) treated with temozolomide, irinotecan, and bevacizumab (TIB) following radiation.
Summary: This study analyzes the safety and effectiveness of valproic acid (VPA) combined with radiation, followed by valproic acid and bevacizumab as a treatment for children with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG).
Summary: This study aims to monitor and treat neurological symptoms in patients with diffuse intrinsic pontine glioma (DIPG) undergoing radiation therapy. The presence of various neurological symptoms was reviewed before and weekly during radiation therapy (RT) for all patients. The amount of change for each symptom was evaluated and compared with the accumulated radiation dose.
Summary: In this study, researchers evaluated the safety and effectiveness of veliparib with radiation and temozolomide for the treatment of diffuse pontine glioma.
Summary: This study determined the maximum tolerated dose, toxicities, and response of sirolimus combined with oral metronomic therapy in pediatric patients with recurrent and refractory solid and brain tumors.
Summary: This study evaluated 6-month progression-free survival (PFS) following administration of nimotuzumab in combination with external beam radiotherapy (RT) in the treatment of diffuse intrinsic pontine glioma (brain tumors; DIPG) in children.
Summary: This study is aimed at exploring the role of intensive, including marrow-ablative, chemotherapy regimens in the treatment of young children with newly-diagnosed high-grade brainstem glioma (BSG). The children were pre-treated with 4-5 induction cycles of one of three intensive chemotherapy regimes followed by Consolidation with one cycle of marrow-ablative chemotherapy (thiotepa, carboplatin and e...