Cardiac Magnetic Resonance for Risk Stratification in Dilated Cardiomyopathy

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Dilated cardiomyopathy (DCM) is an increasingly recognized cause of morbidity and mortality with heterogenous etiologies (eg, genetic, environment) and clinical manifestations, characterized by left ventricular (LV) systolic dysfunction and LV or biventricular dilation. Previous publications reported the three-year treated mortality rates remain high at 12%-20% and a reported 5-year mortality rate up to 50%, with death resulting from ventricular arrhythmia leading to sudden cardiac death (SCD) or advanced heart failure (HF). With large fields of view and high spatial resolution, Cardiac magnetic resonance (CMR) is the reference standard for assessing cardiac mass, volume, and function. CMR also provides non noninvasive characterization of the myocardium benefiting to differential diagnosis and risk stratification.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• reduced left ventricular ejection fraction (LVEF\<50%)

• LV end-diastolic volume \>2SD from normal according to normograms corrected by body surface area (BSA) and age.

Locations
Other Locations
China
Fuwai Hospital
RECRUITING
Beijing
Contact Information
Primary
Minjie Lu, PhD
coolkan@163.com
+86-10-88396941
Time Frame
Start Date: 2019-12-24
Estimated Completion Date: 2031-12-31
Participants
Target number of participants: 2500
Sponsors
Leads: Chinese Academy of Medical Sciences, Fuwai Hospital

This content was sourced from clinicaltrials.gov