PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients) - Investigating Matching, Biomarkers and Outcomes.
Status: Recruiting
Location: See all (6) locations...
Study Type: Observational
SUMMARY
The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation. The participants are included in of of two cohorts. One includes women pregnant after oocyte donation whereas the other includes women pregnant after IVF treatment with autologous oocytes. Participants will be followed throughout pregnancy with blood samples, blood pressure, clinical controls and ultrasound examinations. Clinical outcomes will be registered post-partum.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Age \> 18 years
• BMI \< 35 kg/m2
• Normal wet smear within the past three years
• Both nulli- and multiparous
• Singletons and multiple gestations
Locations
Other Locations
Denmark
Copenhagen Fertility Center
RECRUITING
Copenhagen
Trianglen Fertility Clinic
RECRUITING
Hellerup
Fertility Clinic, Herlev / Gentofte Hospital
RECRUITING
Herlev
Fertility Clinic, Rigshospitalet
RECRUITING
København Ø
Sellmer Klinik
RECRUITING
København S
Aleris Fertility
RECRUITING
Søborg
Time Frame
Start Date: 2024-10-21
Estimated Completion Date: 2028-06-01
Participants
Target number of participants: 462
Treatments
Preg OD
Women pregnant after treatment with oocyte donation
Preg IVF
Women pregnant after IVF treatment with autologous oocytes
Related Therapeutic Areas
Sponsors
Collaborators: Ferring Pharmaceuticals, Gedeon Richter Ltd.
Leads: Copenhagen University Hospital, Hvidovre