Radiosurgery for the Treatment of Refractory Ventricular Extrasystoles and Tachycardias (RAVENTA)
Patients with refractory ventricular extrasystoles or tachycardia not eligible for catheter ablation will receive single fraction stereotactic body radiation therapy (cardiac radiosurgery) with 25 Gy. Investigators initiated this study to demonstrate that in at least 70% of the patients the planned cardiac radiosurgery may be performed without any interruption or treatment related interventional events within the first 30 days after treatment.
• Patients with structural heart disease and implantable cardioverter defibrillator (ICD)
• Age \> 18 years
• either
‣ Recurring symptomatic monomorphic ventricular tachycardia that requires ICD intervention (e.g. shock or anti-tachycardia stimulation). At least 3 episodes within the 3 months prior to inclusion or
⁃ induction of symptomatic monomorphic ventricular tachycardia that requires ICD intervention (e.g. shock or anti-tachycardia stimulation). Induction triggered by ICD or during electrophysiology studies (EPS) or both, a) and b)
• Refractory to antiarrhythmic combination therapy
• Beside the cardiac conditions: No competing illness that would additionally limit the life expectancy to less than 6 months
• No prior radiation therapy in the thorax area
• No pregnancy and no active breastfeeding
• Ability to consent and consent to study participation