Encephalitis Clinical Trials

Find Encephalitis Clinical Trials Near You

Cohort Study on Neuroimmune Diseases in the Reproductive Age

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Neuroimmune diseases are more prevalent among women of reproductive age. Studies have shown that neuroimmune diseases may impact fertility. Therefore, effective management of neuroimmune diseases during pregnancy is particularly important. This study included a follow-up period of up to five years in patients with pregnancy-associated neuroimmune disorders. Data collected included relapse frequency, symptomatology, imaging findings, treatment regimens, peripheral blood profiles, EDSS scores, and MRI results. In addition, maternal drug concentrations, postpartum relapse rates, and neonatal development were monitored after delivery. Following the successful completion of the five-year follow-up, the research team plans to continue the prospective epidemiological study with ten-year follow-up phases. The aim of this study is to generate detailed clinical data on pregnancy-associated autoimmune diseases and to equip clinicians with evidence-based strategies for optimizing disease management during the reproductive age.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 20
Maximum Age: 55
Healthy Volunteers: t
View:

• Patient Group: A total of fifty participants are expected to be enrolled.

∙ Women aged 20-55 years with childbearing potential.

‣ Voluntary informed consent.

‣ Availability of complete personal information.

‣ A confirmed diagnosis of neuromyelitis optica spectrum disorder (NMOSD), multiple sclerosis (MS), autoimmune encephalitis, myasthenia gravis, Guillain-Barré syndrome, or myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).

• Healthy Control Group: A total of fifty healthy women are expected to be included.

⁃ Age- and sex-matched women of childbearing age with plans for pregnancy

⁃ Voluntary informed consent.

⁃ Availability of complete personal information.

Locations
Other Locations
China
The Third Affiliated Hospital, Sun Yat-sen University
RECRUITING
Guangzhou
Contact Information
Primary
Wei Qiu, Ph.D
qiuwei120@vip.163.com
15899968330
Time Frame
Start Date: 2024-04-21
Estimated Completion Date: 2030-04
Participants
Target number of participants: 100
Treatments
Patient group
Patient group: Age-matched women with neuroimmune diseases and fertility plans were recruited from the Fertility and Neuroimmune Diseases Multidisciplinary Outpatient Clinic of the Third Affiliated Hospital, Sun Yat-sen University for epidemiological investigation and clinical prospective study.
Healthy control group
Healthy control group: Age-matched healthy women planning pregnancy were recruited from the Department of Obstetrics at the Third Affiliated Hospital, Sun Yat-sen University for epidemiological and prospective clinical investigation.
Sponsors
Leads: Third Affiliated Hospital, Sun Yat-Sen University

This content was sourced from clinicaltrials.gov