Prospective Pilot Study Evaluating the Prognostic Impact of a Neuro-vascular Examination Associated with Cerebral MRI in the Acute Phase of Infectious Endocarditis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Infectious endocarditis (IE) is a serious condition with an annual incidence of 3 to 10 per 100,000 people. Brain infarctions complicate approximately 20-40% of endocarditis. Brain MRI can detect the presence of recent ischemic lesions and asymptomatic microbleeds. Preoperative brain imaging is part of the recommended assessment in the management of IEs, but the type of imaging and sequences are not codified and the impact of cerebral and vascular imaging findings on the therapeutic decision remains uncertain. The level of evidence of the recommendations remains low, especially for complicated IEs of stroke. There is very little neurological clinical data on patients with IEs. Similarly, neurologists do not systematically participate in multidisciplinary meetings during the management of an IE. It therefore seems interesting to carry out a neurological cohort of this population and to evaluate what would be the contribution of vascular neurologists in the management of infectious endocarditis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult patients

• Certain infectious endocarditis according to Dukes Criteria

• Signed informed consent

Locations
Other Locations
France
Stroke Unit, Pierre Wertheimer hospital, GHE Hospices Civils de Lyon
RECRUITING
Bron
Contact Information
Primary
Elodie ONG, Dr
elodie.ong@chu-lyon.fr
04 72 35 78 18
Backup
Julia CANTERINI
julia.canterini@chu-lyon.fr
04 27 85 66 28
Time Frame
Start Date: 2023-04-06
Estimated Completion Date: 2026-07
Participants
Target number of participants: 110
Treatments
Other: Neurological cohort
All patients included in the study wil have a neurological examination
Related Therapeutic Areas
Sponsors
Leads: Hospices Civils de Lyon

This content was sourced from clinicaltrials.gov