Directional Versus Nondirectional Deep Brain Stimulation of the VIM Thalamic Nucleus for Essential Tremor: Assessment of Therapeutic Window, Speech, Gait and Balance
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for the treatment of essential tremor (ET), effectively treats ET, and minimizes effects on speech, gait and balance compared to nondirectional DBS.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• A tremor syndrome of bilateral upper limb action tremor with at least 3 years' duration
Locations
United States
Oregon
Oregon Health & Science University
RECRUITING
Portland
Contact Information
Primary
Zoe Fanning
fanningz@ohsu.edu
503-494-7772
Time Frame
Start Date: 2021-04-01
Estimated Completion Date: 2029-10-01
Participants
Target number of participants: 24
Treatments
Active_comparator: Directional deep brain stimulation
Deep brain stimulation delivered in a directional manner within an axial plane
Active_comparator: Nondirectional deep brain stimulation
Deep brain stimulation delivered in a nondirectional manner within an axial plane
Related Therapeutic Areas
Sponsors
Leads: Oregon Health and Science University