Familial Dilated Cardiomyopathy Overview
Learn About Familial Dilated Cardiomyopathy
View Main Condition: Cardiomyopathy
Familial dilated cardiomyopathy is a genetic form of heart disease. It occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure.
Mutations in more than 30 genes have been found to cause familial dilated cardiomyopathy. These genes provide instructions for making proteins that are found in cardiac muscle cells called cardiomyocytes.
It is estimated that 750,000 people in the United States have dilated cardiomyopathy; roughly half of these cases are familial.
Familial dilated cardiomyopathy has different inheritance patterns depending on the gene involved.
Brahma Sharma is a Cardiologist and an Interventional Cardiologist in Pittsburgh, Pennsylvania. Dr. Sharma and is rated as an Experienced provider by MediFind in the treatment of Familial Dilated Cardiomyopathy. His top areas of expertise are Atrial Fibrillation, Atrial Myxoma, Familial Dilated Cardiomyopathy, and Heart Tumor.
Anju Arora is an Internal Medicine provider in Pittsburgh, Pennsylvania. Dr. Arora and is rated as an Experienced provider by MediFind in the treatment of Familial Dilated Cardiomyopathy. Her top areas of expertise are Osteopenia, Melorheostosis with Osteopoikilosis, Melorheostosis, and Idiopathic Edema.
Cardiovascular Disease Specialists Of Pittsburgh PC
Ricci Minella is a Cardiologist in Pittsburgh, Pennsylvania. Dr. Minella and is rated as an Experienced provider by MediFind in the treatment of Familial Dilated Cardiomyopathy. His top areas of expertise are Coronary Heart Disease, Atherosclerosis, Angina, High Cholesterol, and Bone Marrow Aspiration.
Summary: Prospective, multicenter, randomized, placebo-controlled, double-blind clinical trial to evaluate safety and efficacy of candesartan in the prevention of the development of Dilated Cardiomyopathy (DCM) in genetic carriers of a DCM-causing variant without disease expression (asymptomatic)
Summary: Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease process can be subtle, but sufficient enough, so that the first event is sudden death. The Mayo Clinic ...
Published Date: April 01, 2017
Published By: National Institutes of Health