Familial Glucocorticoid Deficiency Overview
Learn About Familial Glucocorticoid Deficiency
Familial glucocorticoid deficiency is a condition that occurs when the adrenal glands, which are hormone-producing glands located on top of each kidney, do not produce certain hormones called glucocorticoids. These hormones, which include cortisol and corticosterone, aid in immune system function, play a role in maintaining normal blood sugar (glucose) levels, help trigger nerve cell signaling in the brain, and serve many other purposes in the body.
Mutations in the MC2R, MRAP, and NNT genes account for the majority of cases of familial glucocorticoid deficiency; mutations in other genes, some known and some unidentified, can also cause this condition.
The prevalence of familial glucocorticoid deficiency is unknown.
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
Lehigh Valley Physician Group
Robert Mccauley is an Endocrinologist in Allentown, Pennsylvania. Dr. Mccauley and is rated as a Distinguished provider by MediFind in the treatment of Familial Glucocorticoid Deficiency. His top areas of expertise are Hypoaldosteronism, Glucocorticoid Resistance, Familial Glucocorticoid Deficiency, and Triple A Syndrome.
Grand View Hospital
Vasudev Magaji is an Endocrinologist in Lansdale, Pennsylvania. Dr. Magaji and is rated as an Experienced provider by MediFind in the treatment of Familial Glucocorticoid Deficiency. His top areas of expertise are Thyroid Cancer, Thyroid Nodule, Ectopic Cushing's syndrome, and Papillary Thyroid Cancer.
Abington Memorial Hospital
Glenn Mcgrath is an Endocrinologist in Lansdale, Pennsylvania. Dr. Mcgrath and is rated as an Experienced provider by MediFind in the treatment of Familial Glucocorticoid Deficiency. His top areas of expertise are Obesity in Children, Hyperparathyroidism, Parathyroid Hyperplasia, and Familial Isolated Hyperparathyroidism.
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Published Date: February 01, 2015
Published By: National Institutes of Health