Self-regulation of Real-time fMRI Brain Activity in Chronic Pain: A Potential Neurobiological Mechanism of Cognitive Behavioral Therapy
This study aims to explore the usefulness of self-regulation of brain activity in patients with fibromyalgia. Patients will use real-time functional magnetic resonance imaging (fMRI) neurofeedback to observe and regulate their own brain activity while applying mental strategies to reduce fibromyalgia pain. The study consists of 2 magnetic resonance imaging (MRI) visits that involve brain neuroimaging for fMRI neurofeedback tasks, as well as 8 weekly intervention sessions with a pain psychologist. Patients will be randomized to either Cognitive Behavioral Therapy (CBT) or Fibromyalgia Education groups.
• Aged 18-65
• Meet the Wolfe et al 2011 research criteria for fibromyalgia for at least one year
• On stable doses of medication prior to entering the study and agree not to change medications or dosages (or CAM treatments) during the trial
• Baseline pain intensity of at least 4/10 on average and pain report for at least 50% of days
• Able to provide written consent and fluent in English