Gastroesophageal Reflux in Infants
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Learn About Gastroesophageal Reflux in Infants

What is the definition of Gastroesophageal Reflux in Infants?

Gastroesophageal reflux occurs when stomach contents leak backward from the stomach into the esophagus. This causes "spitting up" in infants.

What are the alternative names for Gastroesophageal Reflux in Infants?

Reflux - infants

What are the causes of Gastroesophageal Reflux in Infants?

When a person eats, food passes from the throat to the stomach through the esophagus. The esophagus is called the food pipe or swallowing tube.

A ring of muscle fibers prevents food at the top of the stomach from moving up into the esophagus. These muscle fibers are called the lower esophageal sphincter, or LES. If this muscle does not close well, food can leak back into the esophagus. This is called gastroesophageal reflux.

A small amount of gastroesophageal reflux is normal in young infants. However, ongoing reflux with frequent vomiting can irritate the esophagus and make the infant fussy. Severe reflux that causes weight loss or breathing problems is not normal.

What are the symptoms of Gastroesophageal Reflux in Infants?

Symptoms may include:

  • Cough, especially after eating
  • Excessive crying as if in pain
  • Excessive vomiting during the first few weeks of life; worse after eating
  • Extremely forceful vomiting
  • Not feeding well
  • Refusing to eat
  • Slow growth
  • Weight loss
  • Wheezing or other breathing problems
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What are the current treatments for Gastroesophageal Reflux in Infants?

Often, no feeding changes are needed for infants who spit up, but are growing well and seem otherwise content.

Your provider may suggest simple changes to help the symptoms such as:

  • Burp the baby after drinking 1 to 2 ounces (oz) or 30 to 60 milliliters (mL) of formula, or after feeding on each side if breastfeeding.
  • Add 1 tablespoon (tbsp.) or 2.5 grams (g) of rice cereal to 2 oz or 60 mL of formula, milk, or expressed breast milk. If needed, change the nipple size or cut a small x in the nipple.
  • Hold your baby upright for 20 to 30 minutes after feeding.
  • Raise the head of the crib. However, your infant should still sleep on their back, unless your provider suggests otherwise.

When your infant begins to eat solid food, feeding thickened foods may help.

Medicines can be used to reduce acid or increase the movement of the intestines.

Who are the top Gastroesophageal Reflux in Infants Local Doctors?
Elite in Gastroesophageal Reflux in Infants
Pediatric Gastroenterology
Elite in Gastroesophageal Reflux in Infants
Pediatric Gastroenterology
Referral may be required

Division Of Gastroenterology, Hepatology And Nutrition

300 Longwood Ave, 
Boston, MA 
Languages Spoken:
English
Accepting New Patients

Rachel Rosen is a Pediatric Gastroenterologist practicing medicine in Boston, Massachusetts. Dr. Rosen is rated as an Elite provider by MediFind in the treatment of Gastroesophageal Reflux in Infants. She is also highly rated in 14 other conditions, according to our data. Her clinical expertise encompasses Gastroesophageal Reflux Disease (GERD), Gastroesophageal Reflux in Infants, Swallowing Difficulty, Gastrostomy, and Myringotomy. Dr. Rosen is currently accepting new patients.

Elite in Gastroesophageal Reflux in Infants
Elite in Gastroesophageal Reflux in Infants
Referral may be required
Naples, IT 

Annamaria Staiano practices practicing medicine in Naples, Italy. Ms. Staiano is rated as an Elite expert by MediFind in the treatment of Gastroesophageal Reflux in Infants. She is also highly rated in 17 other conditions, according to our data. Her clinical expertise encompasses Gastroesophageal Reflux in Infants, Viral Gastroenteritis, Chronic Idiopathic Constipation (CIC), Endoscopy, and Ileostomy.

 
 
 
 
Learn about our expert tiers
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Elite in Gastroesophageal Reflux in Infants
Elite in Gastroesophageal Reflux in Infants
Referral may be required

Universitair Ziekenhuis Brussel

Brussels, BRU, BE 

Yvan Vandenplas practices practicing medicine in Brussels, Belgium. Mr. Vandenplas is rated as an Elite expert by MediFind in the treatment of Gastroesophageal Reflux in Infants. He is also highly rated in 13 other conditions, according to our data. His clinical expertise encompasses Gastroesophageal Reflux in Infants, Gastroesophageal Reflux Disease (GERD), Diarrhea, Grass Allergy, and Endoscopy.

What is the outlook (prognosis) for Gastroesophageal Reflux in Infants?

Most infants outgrow this condition. Rarely, reflux continues into childhood and causes esophageal damage.

What are the possible complications of Gastroesophageal Reflux in Infants?

Complications may include:

  • Aspiration pneumonia caused by stomach contents passing into the lungs
  • Irritation and swelling of the esophagus
  • Scarring and narrowing of the esophagus
When should I contact a medical professional for Gastroesophageal Reflux in Infants?

Contact your provider if your baby:

  • Is vomiting forcefully and often
  • Has other symptoms of reflux
  • Has problems breathing after vomiting
  • Is refusing food and losing or not gaining weight
  • Is crying often
What are the latest Gastroesophageal Reflux in Infants Clinical Trials?
Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

Summary: Bronchopulmonary Dysplasia (BPD), or chronic lung disease of prematurity, is the most consequential complication of preterm birth and is strong predictor of childhood pulmonary and neurodevelopmental disability, particularly in infants diagnosed with grade 3 BPD (ventilator dependence at 36 weeks' postmenstrual age), the most severe disease form. This study aims to (1) generate the first empirical...

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Pilot Trial Comparing Transpyloric to Gastric Feeding in Very Preterm Infants With Bronchopulmonary Dysplasia

Summary: The goal of this clinical trial is to learn if transpyloric tube feeding (feeding directly into the small intestine) versus gastric tube feeding tolerably and effectively reduces gastroesophageal reflux in infants born premature who have been diagnosed with bronchopulmonary dysplasia. The main questions this trial aims to answer are: Does transpyloric as compared to gastric tube feeding result in ...

Who are the sources who wrote this article ?

Published Date: July 01, 2025
Published By: Charles I. Schwartz, MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Hibbs AM. Gastrointestinal reflux and motility in the neonate. In: Martin RJ, Fanaroff AA, eds. Fanaroff and Martin's Neonatal-Perinatal Medicine. 12th ed. Philadelphia, PA: Elsevier; 2025:chap 86.

Khan S, Matta SKR. Gastroesophageal reflux disease. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 369.

Marcdante KJ, Kliegman RM, Schuh AM. Esophagus and stomach. In: Marcdante KJ, Kliegman RM, Schuh AM, eds. Nelson Essentials of Pediatrics. 9th ed. Philadelphia, PA: Elsevier; 2023:chap 128.