Growth Hormone Resistance of Beta-cells in People With a Family History of Type 2 Diabetes
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a family history of type 2 diabetes at the University of Missouri. Our aim is to advance understanding of how growth hormone affects beta-cells and risk factors for developing gestational diabetes and type 2 diabetes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:
• 18 to 45 years old
• hemoglobin HbA1c ≤5.6% and fasting blood glucose \<100 mg/dl
• body mass index ≥30.0 kg/m2 and \<45.0 kg/m2
⁃ Additional, group-specific inclusion criteria:
• Family history of type 2 diabetes: first degree relative with type 2 diabetes
• Control group: no family history of type 2 diabetes
Locations
United States
Missouri
University of Missouri School of Medicine
RECRUITING
Columbia
Contact Information
Primary
Amanda Heider
ahmc4@health.missouri.edu
573-884-6852
Backup
Vasavi Shabrish, PhD
v.shabrish@missouri.edu
Time Frame
Start Date: 2025-07-15
Estimated Completion Date: 2030-09-01
Participants
Target number of participants: 30
Treatments
Men and women with a family history of type 2 diabetes
Men and women without a family history of type 2 diabetes
Related Therapeutic Areas
Sponsors
Leads: University of Missouri-Columbia