The Effect of Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients Using Brimonidine 0.2%, 0.15%, or 0.1%

Who is this study for? Patients with Glaucoma
What treatments are being studied? Brimonidine Tartrate Ophthalmic Solution 0.025%
Status: Not_yet_recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at lowering intraocular pressure while minimizing medication side effects. Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) is an FDA-approved medication for alleviating eye redness, a common side effect of glaucoma medications. The purpose of this study is to evaluate the effect of Lumify™ on eye redness, intraocular pressure, and eyelid position in patients with glaucoma who are already using the Brimonidine 0.1%, 0.15% or 0.2% eye drops.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age \> 18 years

• Diagnosis of primary open angle glaucoma

• Willing and able to give informed consent

• Current and greater than 6 weeks of brimonidine 0.2%, 0.15% or 0.1% use

Locations
United States
Louisiana
Tulane University Medical Center
New Orleans
Contact Information
Primary
Ze Zhang, MD
zzhang9@tulane.edu
504-988-5831
Backup
Whitley Richardson
wrichardson@tulane.edu
504-988-2261
Time Frame
Start Date: 2026-11-10
Completion Date: 2036-06-01
Participants
Target number of participants: 60
Treatments
Experimental: Lumify Arm
In each subject, each eye will be randomized to receive a single drop of either Lumify™ (brimonidine tartrate ophthalmic solution 0.025%) or a sterile balanced saline solution.
Sham_comparator: Control Arm
In each subject, each eye will be randomized to receive a single drop of either Lumify™ (brimonidine tartrate ophthalmic solution 0.025%) or a sterile balanced saline solution.
Sponsors
Leads: Tulane University

This content was sourced from clinicaltrials.gov