Effect of High-Intensity Interval Training, Moderate Continuous Training, or Guideline-Based Physical Activity on Peak Oxygen Uptake and Myocardial Fibrosis in Patients With Myocardial Infarction: Protocol for a Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will investigate the effect of a 12-weeks cardiac rehabilitation training (HIIT, MICT) program on VO2peak and cardiac fibrosis in patients, and evaluate the effects of HIIT on endothelial function, microvascular obstruction, body fat, inflammation, arrhythmia and psychology .
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Aged 18 -75 years
• Acute myocardial infarction (AMI) patients between 6 weeks and 3 months and had been underwent revascularization, and New York Heart Association functional classification (NYHA) Class I-III; (AMI confirmed by the World Health Organization definition (presence of symptoms of ischemia and changes in electrocardiogram) or the Third Universal Definition of Myocardial Infarction (elevation of a cardiac biomarker along with presence of either symptoms of myocardial infarction or changes in electrocardiogram))
• Willing and able to attend the complete cardiac rehabilitation(CR)program on their own，assigned the Informed consent form.
• Complete the cardiopulmonary exercise testing (CPET) at enrollment or has the CPET report within 1 month.
Locations
Other Locations
China
Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital
RECRUITING
Guangzhou
Contact Information
Primary
Qingshan Geng
gengqsh@163.net
13922205818
Backup
Huan Ma
mahuan@gdph.org.cn
15018755932
Time Frame
Start Date:2021-05-01
Estimated Completion Date:2025-10-31
Participants
Target number of participants:180
Treatments
Experimental: High Intensity Interval Training(HIIT)
The HIIT sessions include brief, intermittent bouts of high-intensity exercise interspersed with periods of low-intensity exercise (active recovery).HIIT include 20 intervals of high-intensity (30-60s at rating of perceived exertion (RPE; Borg scale of 6-20) of 15 to 17) and low-intensity (1min at RPE \<10 or totally rest). The whole exercise cycle takes around 40-50 minutes.