Cardiovascular Reactivity to Physical Stress: Strategies and Mechanisms

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

It is well-accepted that an exaggerated blood pressure (BP) response to physical stress has a prognostic value, indicating a higher cardiovascular risk (e.g., sudden cardiac death, myocardial infarction, future hypertension, and left ventricular hypertrophy). However, there is a limited understanding of the underlying mechanisms and therapuetic strategies modulating this response. Therefore, this pilot project aims to explore whether one session of low-volume high-intensity interval training (low-volume HIIT) or combined intermittent heat and cold bath (sauna+cold bath) can decrease BP responses to physical stress. Furthermore, the secondary goal is to investigate whether one brief session learning about positive stress expectations magnifies the decrease in BP following low-volume HIIT and sauna+ cold bath.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:

• Male or female between 18 to 50 years

• Non-smoker.

• Non-obese (\<30 kg/m2).

• Able to walk on a treadmill and cycle on a stationary bike without problems.

• No or little (frequency \< 2 times per month) experience swimming with sauna and cold water.

• Proficient in Norwegian and able to provide informed consent.

Locations
Other Locations
Norway
Western Norway University of Applied Sciences
RECRUITING
Bergen
Contact Information
Primary
Ann-Katrin Grotle, PhD
ann-katrin.grotle@hvl.no
+4790960580
Backup
Hege R Eriksen, PhD
hege.randi.eriksen@hvl.no
Time Frame
Start Date: 2024-02-19
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 58
Treatments
Experimental: Positive stress education (PSE)
This intervention will consist of standardized information about the relationships between expectations and the stress response. Using the CATS as a theoretical framework, the participants will be explained that when people face stressors, i.e., pain, heat, and cold water, the expectations about handling the situation will influence both the experience (e.g., pain) and the physiological stress response.
Sham_comparator: Neutral control
To control for the PSE intervention, the participants will receive 15 min of neutral information about the effects of physical exercise on cardiovascular fitness.
Sponsors
Leads: Western Norway University of Applied Sciences

This content was sourced from clinicaltrials.gov

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