Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking Study

Status: Recruiting
Study Type: Observational
SUMMARY

This prospective, multicenter observational study aims to evaluate the incidence, timing, and characteristics of residual and recurrent (restenosis) carotid artery stenosis following carotid endarterectomy (CEA) with primary closure. Conducted across several neurosurgical centers in the Czech Republic, the study will include patients undergoing elective CEA who meet standard clinical indications. Participants will undergo preoperative CT angiography and follow-up imaging at 30 days and 1 year post-surgery. Residual stenosis is defined as ≥50% luminal narrowing detected within 30 days postoperatively, while restenosis is evaluated at later time points. The study will also assess clinical outcomes such as ischemic stroke, TIA, myocardial infarction, and mortality. The standardized surgical technique and harmonized diagnostic algorithm across all centers aim to provide robust data on the performance and durability of primary closure CEA.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:

• Patients without matching any of exclusion criteria who underwent cartotid endarterectomy

Contact Information
Primary
norbert Svoboda, MD
norbert.svoboda@uvn.cz
+420973202963
Time Frame
Start Date: 2025-02-01
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 300
Treatments
Patients after carotid endarterectomy
Included paitnets with sign informed consent after carotid endarterectomy
Sponsors
Collaborators: The University Hospital Plzeň, County Hospital Liberec, Liberec, Czech Republic, Masaryk Hospital Usti nad Labem, University Hospital Olomouc
Leads: Charles University, Czech Republic

This content was sourced from clinicaltrials.gov

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