The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With Heart Failure With Preserved Ejection Fraction
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is trying to find out how best to improve common measures of health and survival in those diagnosed with heart failure with preserved ejection fraction (HFpEF) through the implementation of 4 weeks of an exercise training program consisting of high intensity interval training, dietary approaches to stop hypertension (DASH diet), or a combination of the two. Currently there are not established guidelines that have been shown to improve clinical end points in those with this HFpEF.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:
• ≥40 years of age
• Diagnosed with heart failure with preserved ejection fraction
• NYHA class II-III symptoms
• Physician clearance to undergo exercise training
• Physician clearance to consume DASH diet
• Complete COVID-19 vaccination status
Locations
United States
Virginia
University of Virginia University Hospital
RECRUITING
Charlottesville
Contact Information
Primary
Siddhartha S Angadi, PhD
ssa2w@virginia.edu
434-243-7466
Backup
Nathan Weeldreyer, MS
nw8ky@virginia.edu
434-243-8677
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2025-08-01
Participants
Target number of participants: 36
Treatments
Experimental: High Intensity Interval Exercise
Enrolled patients will perform supervised exercise on 3 nonconsecutive days of the week for 4 weeks.
Experimental: Dietary Approaches to Stop Hypertension (DASH) Diet
Enrolled patients will have all of their food prepared for them by a registered dietician for the duration of the study period. The diet will consist of a high fiber content DASH diet.
Experimental: Exercise + DASH Diet
Enrolled subjects will undergo both the exercise training visits and be provided with the DASH diet.
Related Therapeutic Areas
Sponsors
Leads: University of Virginia
Collaborators: Grain Foods Foundation