Cardiovascular Magnetic Resonance Prognosticators In Pediatric Oncology Patients With Sepsis: A Priority Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Objectives: (Feasibility Phase) To determine the feasibility of cardiac MRI without anesthesia in the immediate post-sepsis period in children with cancer. CMR scanning will be completed within 10 days of presentation - this will allow us to ensure that possible hemodynamic or respiratory instability and renal dysfunction has resolved prior to transport to the MRI scanner during the most acute phase of illness. (Completion Phase) To estimate the frequency of subacute sepsis-associated cardiac disease, including myocardial inflammation and dysfunction, in the post-acute phase (within 10 days of presentation) of severe sepsis in children with cancer

Eligibility
Participation Requirements
Sex: All
Minimum Age: 9
Maximum Age: 25
Healthy Volunteers: f
View:

• Between 9 and 25 years of age at time of study enrollment

• Currently receiving care for cancer at St. Jude

• Diagnosed with sepsis according to Phoenix score

Locations
United States
Tennessee
St. Jude Children's Research Hospital
RECRUITING
Memphis
Contact Information
Primary
Anthony Merlocco, MD
amerlocc@uthsc.edu
866-870-5570
Backup
Joshua Wolf, MBBS. PhD
joshua.wolf@stjude.org
866-870-5570
Time Frame
Start Date: 2023-05-20
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 20
Treatments
Experimental: Cardiac MRI after sepsis
Participants who meet the eligibility criteria of severe sepsis.
Sponsors
Leads: St. Jude Children's Research Hospital

This content was sourced from clinicaltrials.gov