Prognostic Impact of Non-invasive Imaging Parameters (Cardiac Echocardiography and MRI) in Patients With Primary Mitral Insufficiency (MI) by Prolapse: Observational Cohort, Monocentric (COHORTE-IM)

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Degenerative mitral insufficiency secondary to valve prolapse is the most common valve disease in Western countries. In the absence of specific treatment, it spontaneously progresses to heart failure and death when it is severe. Surgical mitral valve repair (or mitral plastic surgery) is the preferred treatment for primary mitral insufficiency by prolapse in case of severe leakage if associated with clinical and/or echocardiographic markers of poor prognosis (i.e., with high risk of morbi-mortality during their follow-up). It is therefore essential to refine the risk stratification of these patients in order to identify at-risk patients who should potentially benefit earlier from invasive care (cardiac surgery), or conversely, close monitoring. A number of echocardiographic and MRI parameters may have been associated with a poorer prognosis. A cohort of patients with primary mitral insufficiency (MI) will be followed to study the relationships of a set of factors to patient prognosis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:

• Any patient with primary mitral insufficiency by prolapse (any grade) diagnosed by Trans-Thoracic Echocardiography (TTE)

• From November 2010 to April 2019 (retrospective cohort)

• From May 2019 to May 2024 (prospective cohort)

• No previous surgery of the mitral valve before the first ultrasound

• Adults

• Patient who has been informed and not opposed to the use of his or her medical record data

Locations
Other Locations
France
Lille Catholic Hospitals
RECRUITING
Lomme
Contact Information
Primary
Marie Paule LEBITASY, Md
lootens.livia@ghicl.net
+33 3 20 22 52 69
Backup
Audrey TOIA, CRA
toia.audrey@ghicl.net
+33 3 20 22 57 33
Time Frame
Start Date: 2019-09-04
Estimated Completion Date: 2034-09
Participants
Target number of participants: 400
Treatments
Patient cohort
Routine follow-up of patients in the Cardiological Functional Explorations department - Valve Disease Centre for their primary mitral insufficiency by prolapse
Sponsors
Leads: Lille Catholic University
Collaborators: University Hospital, Lille

This content was sourced from clinicaltrials.gov