Mitral Valve Prolapse
Symptoms, Doctors, Treatments, Advances & More

Learn About Mitral Valve Prolapse

What is the definition of Mitral Valve Prolapse?

Mitral valve prolapse is a heart problem involving the mitral valve, which separates the upper and lower chambers of the left side of the heart. In this condition, the valve does not close normally.

What are the alternative names for Mitral Valve Prolapse?

Barlow syndrome; Floppy mitral valve; Myxomatous mitral valve; Billowing mitral valve; Systolic click-murmur syndrome; Prolapsing mitral leaflet syndrome; Chest pain - mitral valve prolapse

What are the causes of Mitral Valve Prolapse?

The mitral valve helps blood on the left side of the heart flow in one direction. It closes to keep blood from moving backwards when the heart beats (contracts).

Mitral valve prolapse is the term used when the valve does not close properly. It can be caused by many different things.

In most cases, it is harmless. The problem generally does not affect health and most people with the condition are not aware of it. In a small number of cases, the prolapse can cause blood to leak backwards. This is called mitral regurgitation.

Mitral valve prolapse often affects thin women who may have minor chest wall deformities, scoliosis, or other disorders. Some forms of mitral valve prolapse seem to be passed down through families (inherited).

Mitral valve prolapse is also seen with some connective tissue disorders such as Marfan syndrome and other rare genetic disorders.

It is also sometimes seen in isolation in people who are otherwise normal.

What are the symptoms of Mitral Valve Prolapse?

Many people with mitral valve prolapse Do not have symptoms. A group of symptoms sometimes found in people with mitral valve prolapse has been called "mitral valve prolapse syndrome," and includes:

  • Chest pain (not caused by coronary artery disease or a heart attack)
  • Dizziness
  • Fatigue
  • Panic attacks
  • Sensation of feeling the heart beat (palpitations)
  • Shortness of breath with activity or when lying flat (orthopnea)

The exact relationship is between these symptoms and the valve problem is not clear. Some of the findings may be coincidental.

When mitral regurgitation occurs, symptoms may be related to the leaking, particularly when severe.

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What are the current treatments for Mitral Valve Prolapse?

Most of the time, there are few or no symptoms and treatment is not needed.

In the past, most people with heart valve problems were given antibiotics before dental work or procedures such as colonoscopy to prevent an infection in the heart. However, antibiotics are now used much less often. Check with your provider to see if you need antibiotics.

There are many heart medicines that may be used to treat aspects of this condition. However, most people will not need any treatment. You may need surgery to repair or replace your mitral valve if it becomes very leaky (regurgitation), and if the leakiness also causes symptoms. However, this may not occur. You may need mitral valve repair or replacement if:

  • Your symptoms get worse.
  • The left ventricle of your heart is enlarged.
  • Your heart function gets worse.
Who are the top Mitral Valve Prolapse Local Doctors?
Francesca N. Delling
Elite in Mitral Valve Prolapse
Elite in Mitral Valve Prolapse

Cardiovascular Care And Prevention Center At Mission Bay

535 Mission Bay Blvd. South, 
San Francisco, CA 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Dr. Francesca Nesta Delling is a cardiologist with advanced training in echocardiography (heart ultrasound) and cardiac MRI, in which magnetic energy is used to take diagnostic pictures of the heart. She cares for patients with valvular heart disease, with a focus on mitral valve prolapse (when the valve between the heart's left chambers fails to close completely), cardiomyopathies (diseases of the heart muscle) and sudden cardiac death related to valvular disease. She also provides ultrasound guidance for catheter-based procedures (in which the heart is accessed by threading a catheter – a flexible, hollow tube – through a blood vessel), such as MitraClip, a minimally invasive treatment for leaky mitral valves. Delling's research has focused on why some patients with valve disease progress to more severe stages and develop complications. Her investigations are based on genetic analysis and cardiac imaging techniques, such as echocardiography and cardiac MRI, and she collaborates with researchers across the U.S. and Europe, with funding from the National Institutes of Health. Delling earned her medical degree from the University of Brescia in Italy. She completed a residency in internal medicine at Boston Medical Center, a fellowship in echocardiography at Massachusetts General Hospital and a fellowship in cardiovascular medicine at Beth Israel Deaconess Medical Center. She also has a master of public health degree from the Harvard T.H. Chan School of Public Health. Dr. Delling is rated as an Elite provider by MediFind in the treatment of Mitral Valve Prolapse. Her top areas of expertise are Mitral Valve Prolapse, Mitral Valve Regurgitation, Cardiac Arrest, Cardiac Ablation, and Pacemaker Implantation.

Rakesh Suri
Elite in Mitral Valve Prolapse
Thoracic Surgery
Elite in Mitral Valve Prolapse
Thoracic Surgery

Corewell Health William Beaumont University Hospital Cardiovascular Surgery

3601 West 13 Mile Road, 
Royal Oak, MI 
Experience:
31+ years
Languages Spoken:
English
Accepting New Patients

Rakesh Suri is a Thoracic Surgeon in Royal Oak, Michigan. Dr. Suri has been practicing medicine for over 31 years and is rated as an Elite provider by MediFind in the treatment of Mitral Valve Prolapse. His top areas of expertise are Mitral Valve Regurgitation, Mitral Valve Prolapse, Aortic Valve Stenosis, Aortic Valve Replacement, and Transcatheter Aortic Valve Replacement (TAVR). Dr. Suri is currently accepting new patients.

 
 
 
 
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A M. Gillinov
Elite in Mitral Valve Prolapse
Thoracic Surgery
Elite in Mitral Valve Prolapse
Thoracic Surgery

Cleveland Clinic Main Campus

9500 Euclid Avenue, 
Cleveland, OH 
Experience:
42+ years
Languages Spoken:
English

A Gillinov is a Thoracic Surgeon in Cleveland, Ohio. Dr. Gillinov has been practicing medicine for over 42 years and is rated as an Elite provider by MediFind in the treatment of Mitral Valve Prolapse. His top areas of expertise are Mitral Valve Regurgitation, Mitral Valve Prolapse, Aortic Regurgitation, Heart Valve Repair, and Heart Bypass Surgery.

What is the outlook (prognosis) for Mitral Valve Prolapse?

Most of the time, mitral valve prolapse is harmless and does not cause symptoms. Symptoms that do occur can be treated and controlled with medicine or surgery.

Some abnormal heartbeats (arrhythmias) in people with mitral valve prolapse can be life threatening. If the valve leakage becomes severe, your outlook may be similar to that of people who have mitral regurgitation from any other cause.

When should I contact a medical professional for Mitral Valve Prolapse?

Contact your provider if you have:

  • Chest discomfort, palpitations, or fainting spells that get worse
  • Long-term illnesses with fevers
What are the latest Mitral Valve Prolapse Clinical Trials?
AI-Based Morphological Analysis and Biomechanical Numerical Evaluation of Mitral Valve Prolapse (MVP) From Real-Time 3D Echocardiography (RT3DE)

Summary: This study aims to develop and validate a fully automated imaging and modeling pipeline for the analysis of mitral valve prolapse (MVP) using real-time three-dimensional transesophageal echocardiography (RT3DE). The primary goal is to automatically segment mitral valve (MV) substructures, extract anatomical landmarks, and generate 3D models of the MV apparatus to characterize morphological and fun...

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Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse: the SCIMITAR Trial

Summary: This is a multicenter, observational prospective and retrospective study which aims are: 1) to compute a scoring model potentially predictive for the diagnosis of fibrosis by CMR in patients with MVP; 2) to identify specific features that may predispose to ≥ mild VAs or SCD in patients with MVP.

Who are the sources who wrote this article ?

Published Date: February 27, 2024
Published By: Thomas S. Metkus, MD, Assistant Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Carabello BA, Kodali S. Valvular heart disease. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 60.

Hahn RT, Bonow RO. Mitral regurgitation. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 76.

Writing Committee Members, Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Thorac Cardiovasc Surg. 2021;162(2):e183-e353. PMID: 33972115 pubmed.ncbi.nlm.nih.gov/33972115/.