Effects of Inspiratory Muscle Training Via a Mobile Respiratory Trainer (AiroFit PRO™) on Pulmonary Function, Muscle Strength, and Quality of Life in Hemiplegic Individuals: A Randomized Controlled Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Objective: To investigate and compare the efficacy of a 6-week, supervised respiratory training program using the AiroFit PRO™ mobile respiratory trainer against traditional Pursed-Lips Breathing exercises in individuals with hemiplegia. Study

Design: A single-blind, two-arm, randomized controlled trial. Participants: Ambulatory adults with stable hemiplegia (≥3 months post-stroke), who are medically stable and able to follow commands. Interventions: Participants will be randomly assigned to one of two groups: Experimental Group: Will perform Inspiratory Muscle Training using the AiroFit PRO™ device for 15 minutes/day, 5 days/week, for 6 weeks. The intensity will be progressively increased. Active Control Group: Will perform Pursed-Lips Breathing exercises for an identical duration and frequency. Primary Outcomes: Changes in pulmonary function tests, including Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 second (FEV1), and Maximal Inspiratory Pressure (MIP). Significance: This study will provide high-level evidence on the utility of smart, device-guided respiratory training as a novel component of neurorehabilitation, potentially offering a more effective strategy to improve respiratory health and overall recovery in hemiplegic patients compared to standard breathing exercises.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Clinical Diagnosis: A confirmed diagnosis of unilateral hemiplegia or hemiparesis (e.g., secondary to ischemic or hemorrhagic stroke), sustained at least 3 months prior to enrollment.

• Age: Aged between 18 and 80 years.

• Stable Medical Condition: Medically stable, as determined by the treating physician, with no changes in their primary rehabilitation regimen or medication for spasticity/neurological condition in the past 4 weeks.

• Cognitive \& Communication Ability: Sufficient cognitive function and language comprehension to understand and follow simple commands and provide informed consent, as assessed by a Mini-Mental State Examination (MMSE) score of ≥ 24 (or a similar validated tool).

• Respiratory Status: Able to perform forced expiratory maneuvers for spirometry and tolerate the breathing training protocols.

Locations
Other Locations
Turkey
University of Usak
RECRUITING
Uşak
Contact Information
Primary
Ali Y Karahan, Professor
ali.karahan@usak.edu.tr
+905386921934
Backup
Mustafa Sengul, Asst. Prof.
mustafa.sengul@usak.edu.tr
Time Frame
Start Date: 2025-12-11
Estimated Completion Date: 2026-06-11
Participants
Target number of participants: 54
Treatments
Experimental: Device-Guided Inspiratory Muscle Training (AiroFit™ PRO)
* Device: The AiroFit™ PRO mobile respiratory trainer will be used.~* Principle: The device provides adjustable, pressurized resistance to inhalation and exhalation, with real-time visual feedback provided via a connected smartphone application.~* Procedure:~ 1. Participants will be seated in a comfortable chair.~ 2. The initial training intensity (resistance level) will be set based on the device's calibration feature, which typically starts at 50-60% of the individual's maximal inspiratory pressure (MIP).~ 3. Participants will be instructed to perform slow, deep inspirations through the device, following the visual pacing and targets on the smartphone app.~ 4. The training protocol will consist of structured breathing exercises as per the AiroFit™ PRO's built-in programs, which include cycles of inspiratory load, breath-holds, and expiratory phases.
Active_comparator: Pursed-Lips Breathing Training
* Device: None. This is a non-device, technique-based breathing exercise.~* Principle: Pursed-Lips Breathing (PLB) is a simple breathing technique that involves inhaling through the nose and exhaling slowly and gently through pursed lips, creating back-pressure to keep small airways open.~ * Procedure:~ 1. Participants will be seated in a comfortable chair with their shoulders relaxed.~ 2. They will be instructed by the physiotherapist to:~ 1. Inhale slowly and deeply through the nose for a count of 2 seconds.~ 2. Pucker their lips as if to whistle.~ 3. Exhale slowly and gently through the pursed lips for a count of 4 seconds (aiming for an I:E ratio of 1:2).~ 3. The session will consist of continuous cycles of this breathing pattern for the full 15-minute duration.~ 4. The physiotherapist will provide verbal cues and correction to ensure proper technique throughout the session.
Sponsors
Leads: Uşak University

This content was sourced from clinicaltrials.gov