Hemorrhagic Proctocolitis Clinical Trials

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Nutrition and Body Composition and Association With Clinical Outcomes in Inflammatory Bowel Disease

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to demonstrate that nutritional status and body composition have an impact on clinical outcomes in inflammatory bowel disease (IBD). The main objectives are: 1. To compare the detection rates of undernutrition between a range of nutritional screening tools, physiological measures and assessment tools amongst patients with different IBD phenotypes 2. To correlate nutritional status, nutritional biomarkers and body composition with clinical outcomes in patients with IBD treated with advanced medical therapy or surgery 3. To determine a potential relationship between radiological muscle mass measurements and clinical outcomes in patients with IBD treated with advanced medical therapy or surgery Participants will undergo an assessment at pre-treatment baseline and then again at their scheduled follow-up. This is a non-interventional study and participants will not be required to have any invasive tests or hospital visits beyond that of standard clinical care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:

• Patients with inflammatory bowel disease (Crohn's disease, ulcerative colitis or IBD-U) starting a new advanced medical therapy

• Patients with inflammatory bowel disease (Crohn's disease, ulcerative colitis or IBD-U) undergoing an IBD-related surgery

• Age \>16

• Patients able and willing to provide written informed consent

Locations
Other Locations
United Kingdom
Barts Health NHS Trust
RECRUITING
London
Contact Information
Primary
Sarah Faloon, MBChB
sarah.faloon@nhs.net
07713444631
Backup
Shameer Mehta, MD
shameer.mehta@nhs.net
020 3594 3500
Time Frame
Start Date: 2024-10-24
Estimated Completion Date: 2028-12
Participants
Target number of participants: 300
Treatments
Medical treatment group
Patients with inflammatory bowel disease (Crohn's disease, ulcerative colitis or IBD-U) starting a new advanced medical therapy (e.g. biologic or small molecule)
Surgical treatment group
Patients with inflammatory bowel disease (Crohn's disease, ulcerative colitis or IBD-U) undergoing an IBD-related surgery
Sponsors
Leads: Barts & The London NHS Trust
Collaborators: King's College London

This content was sourced from clinicaltrials.gov