Hereditary Coproporphyria
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Hereditary Coproporphyria Overview

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Learn About Hereditary Coproporphyria

What is the definition of Hereditary Coproporphyria?
Hereditary coproporphyria (HCP) is a rare inherited form of liver (hepatic) porphyria, characterized by neurological symptoms in the form of episodes (acute attacks) of stomach pain, nausea, vomiting, weakness, numbness, and pain in the hands and feet (neuropathy). The porphyrias are a group of blood conditions caused by a lack of an enzyme in the body that makes heme, an important molecule that carries oxygen throughout the body and is vital for all of the body's organs. Symptoms present during the attacks may include body pain, nausea and vomiting, increased heart rate (tachycardia), and high blood pressure. Less common symptoms include seizures, skin lesions, and paralysis of the arms and legs, body trunk, and respiratory muscles. Most individuals with HCP do not have any signs or symptoms between attacks. HCP is caused by genetic changes in the CPOX gene and is inherited in an autosomal dominant manner. Diagnosis is based on the symptoms and specific blood, urine and stool testing.
What are the alternative names for Hereditary Coproporphyria?
  • Hereditary coproporphyria
  • CPO deficiency
  • CPRO deficiency
  • CPX deficiency
  • Coproporphyria
  • Coproporphyria hereditary
  • Coproporphyrinogen oxidase deficiency
  • HCP
  • Hereditary coproporphyria porphyria
  • Porphyria hepatica II
  • Porphyria hepatica coproporphyria
Who are the top Hereditary Coproporphyria Local Doctors?
Distinguished in Hereditary Coproporphyria
Dr. Song Zhao
Oncology
Distinguished in Hereditary Coproporphyria
Dr. Song Zhao
Oncology

Medical Oncology - Swedish Cancer Institute First Hill

1221 Madison Street, 
Seattle, WA 
206-386-3751
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Dr. Zhao believes in providing the best cancer care through multidisciplinary, evidence-based — yet personalized — approaches. Dr. Zhao is rated as a Distinguished provider by MediFind in the treatment of Hereditary Coproporphyria. He is also highly rated in 19 other conditions, according to our data. His clinical expertise encompasses Variegate Porphyria, Hereditary Coproporphyria, Porphyria, and Prostate Cancer. Dr. Zhao is board certified in American Board Of Internal Medicine. Dr. Zhao is currently accepting new patients.

Elite in Hereditary Coproporphyria
Dr. Robert J. Desnick
Medical Genetics | Pediatrics
Elite in Hereditary Coproporphyria
Dr. Robert J. Desnick
Medical Genetics | Pediatrics
1 Gustave L Levy Pl, Box 1498, 
New York, NY 
212-659-6700
Languages Spoken:
English

Robert Desnick is a Medical Genetics specialist and a Pediatrics provider practicing medicine in New York, New York. Dr. Desnick is rated as an Elite provider by MediFind in the treatment of Hereditary Coproporphyria. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Hereditary Coproporphyria, Fabry Disease, Aplasia Cutis Congenita, and Ectodermal Dysplasias.

 
 
 
 
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Elite in Hereditary Coproporphyria
Yonatan Edel
Elite in Hereditary Coproporphyria
Yonatan Edel
Beersheba, D, IL 

Yonatan Edel practices practicing medicine in Beersheba, Israel. Mr. Edel is rated as an Elite expert by MediFind in the treatment of Hereditary Coproporphyria. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Hereditary Coproporphyria, Variegate Porphyria, Porphyria, and Acute Intermittent Porphyria.

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What are the latest Hereditary Coproporphyria Clinical Trials?
Longitudinal Study of the Porphyrias
Longitudinal Study of the Porphyrias
Enrollment Status: Recruiting
Publish Date: January 15, 2026

Summary: The objective of this protocol is to conduct a longitudinal multidisciplinary investigation of the human porphyrias including the natural history, morbidity, pregnancy outcomes, and mortality in people with these disorders.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center