Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed food as medicine intervention designed to lower insulin resistance through healthy food access, food utilization skills, and other self-care behaviors. Knowledge gained from this study can benefit those living with HIV through the prevention and more effective management of pre-diabetes, diabetes, obesity, and non-alcoholic fatty liver disease.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• HIV-positive with income \<400% federal poverty level

• at least 1 risk factor for insulin resistance per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (i.e., overweight/obesity, age 45 yrs or older, immediate family member with diabetes, non-white race, physical inactivity, history of gestational diabetes, history of heart disease or stroke, diagnosis of polycystic ovarian syndrome, high blood pressure, high cholesterol, or hepatitis C virus antibody positivity

• using antiretroviral therapy for at least 6 months

• English-speaking

Locations
United States
Oklahoma
OU Integrative Immunology Center
RECRUITING
Tulsa
Contact Information
Primary
Lacey Caywood, MPH
nourish@tulsacares.org
918-834-4194
Time Frame
Start Date: 2020-10-09
Estimated Completion Date: 2025-12
Participants
Target number of participants: 234
Treatments
Experimental: NOURISH Food Box
12-week food assistance with low Dietary Inflammatory Index (DII) foods
No_intervention: Wait-list Control
Wait-list control group eligible to receive NOURISH box after study period
Sponsors
Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Leads: University of Oklahoma

This content was sourced from clinicaltrials.gov