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Impact of Ehlers-Danlos Syndrome on Gynaecological Health: Focus on the Prevalence of Dysmenorrhoea

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Dysmenorrhea is a common problem in gynaecology, significantly impacting patients' quality of life. Ehlers-Danlos syndrome (EDS) is associated with joint hypermobility, tissue fragility and chronic pain. Some studies suggest an increased prevalence of gynaecological disorders, including dysmenorrhea, in patients with EDS. However, data remain limited and few studies have compared the intensity and characteristics of dysmenorrhea in women with EDS. There is also little data on the prevalence of other gynaecological conditions in women with EDS. This study therefore aims to compare the severity of dysmenorrhea in patients with EDS and a control group in order to better characterise the gynaecological impact of EDS. It will also compare the prevalence of other gynaecological conditions between women with EDS and women without EDS.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:

• Women aged 18 or over.

• Willing to participate voluntarily in the study via an online questionnaire.

• Of childbearing age.

• Reporting a diagnosis of EDS (all types) or not having EDS (control group) and being part of a database of healthy volunteers.

Locations
Other Locations
France
CHU de ROUEN
RECRUITING
Rouen
Contact Information
Primary
Mathilde ML LECOINTRE, Doctor
melodie.lecointre@chu-rouen.fr
02 32 88 07 89
Backup
Constance CB BOHN, Doctor
constance.bohn@chu-rouen.fr
02 32 88 07 89
Time Frame
Start Date: 2025-07-07
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 156
Treatments
Experimental group: women with Ehlers-Danlos syndrome (EDS)
Women with Ehlers-Danlos syndrome (EDS) of all types diagnosed by a healthcare professional
Comparator group: Women not affected by Ehlers-Danlos syndrome (EDS)
Women without Ehlers-Danlos syndrome (EDS) (control group) from a healthy volunteer base
Sponsors
Leads: University Hospital, Rouen

This content was sourced from clinicaltrials.gov