Effect of Combined Transcutaneous Electrical Stimulation and Isometric Exercise on Peripheral Hemodynamic Parameters in Patients With Resistant Hypertension

Status: Recruiting
Location: See location...
Intervention Type: Device, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if the combination between transcutaneous electrical nerve stimulation (TENS) and isometric exercise (IE) can improve blood pressure in men and women between 50 to 60 years old suffered from resistant hypertension which is a type of hypertension where blood pressure remains above your target goal despite the use of three or more different classes of antihypertensive medications at their maximum tolerated doses. The main question to answer is: Is there a significant effect on the combined use of TENS and IE on peripheral hemodynamic parameters in patients with resistant hypertension? Total sample will be 50 patients from both sexes I will compare between two groups: Experimental group (15 men, 10 women) will take: medication plus IE and TENS Control group (15 men, 10 women) will take: medication plus Conventional Physical Therapy Program

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 60
Healthy Volunteers: f
View:

• Age between 50 and 60 years. Both sexes were included Patients had been diagnosed with hypertension for at least 5 years.

⁃ Patients had resistant hypertension according to (Whelton et al 2018), defined as:

• Systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg despite the use of three or more antihypertensive medications of different classes, including a diuretic,

• or controlled blood pressure (\<140/90 mmHg) while on four or more antihypertensive medications.

⁃ Body Mass Index (BMI) 25: 34.9 kg/m²

⁃ Increased waist circumference, defined as:

• Greater than 102 cm for males.

• Greater than 88 cm for females.

Locations
Other Locations
Egypt
Out Clinics of Port Said Hospitals
RECRUITING
Port Said
Contact Information
Primary
Mohamed Mohamed Morgan, Bachelor of Physical Therapy
m.morgan@cu.edu.eg
201026099152
Time Frame
Start Date: 2026-01-15
Estimated Completion Date: 2026-06-10
Participants
Target number of participants: 50
Treatments
Experimental: Combined TENS and Isometric Exercise
Participants in this arm will receive a combined intervention of Transcutaneous Electrical Nerve Stimulation (TENS) and a structured protocol of isometric exercises specifically designed for patients with resistant hypertension.
Active_comparator: Conventional Physical Therapy Program
Participants in this arm will receive a standard conventional physical therapy program. This serves as the active control to compare the effectiveness of the combined TENS and exercise protocol against current standard practice.
Related Therapeutic Areas
Sponsors
Leads: Mohamed Mohamed Ali Morgan

This content was sourced from clinicaltrials.gov