Impact of Thyroid Hormones on Human Glucose and Energy Metabolism
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this clinical trial to clarify the impact of changes in thyroid hormone levels on glucose and lipid metabolism. Patients will be included in whom thyroid hormone levels are intentionally changed by treatment. In patients with Graves' disease, thyroid hormone levels will be lowered using medication, while in patients with thyroid cancer, thyroid hormone levels will be raised using medication. Oral glucose tolerance tests will be performed before treatment and at two time points after treatment begins to assess metabolic effects.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• patients with initial diagnosis of graves disease OR
• patients with initial diagnosis of thyroid carcinoma
Locations
Other Locations
Germany
Ulm University Hospital
RECRUITING
Ulm
Contact Information
Primary
Martin Heni, Prof
martin.heni@uniklinik-ulm.de
+4973150044505
Backup
Roza Sabia, MD
roza.sabia@uniklinik-ulm.de
+4973150044719
Time Frame
Start Date: 2026-02-04
Estimated Completion Date: 2031-06
Participants
Target number of participants: 60
Treatments
Other: Phenotyping Cohort
Patients with Graves' disease and patients with thyroid carcinoma undergoing standard-of-care thyroid treatment.
Related Therapeutic Areas
Sponsors
Leads: University of Ulm