Retrospective Analysis of a Cohort of Duffy-null Associated Neutrophil Count (DANC) Pediatric Patients

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

There are currently no clinical and laboratory data that well characterize this neutropenia associated with the Duffy-null phenotype, particularly for pediatric subjects. In particular there are no data on the frequency of immune neutropenia in DANC neutropenic pediatric subjects. The goal of this study is to : * define the frequency of immune neutropenia within the cohort of DANC subjects under study * evaluate the frequency of different degrees of neutropenia (mild-moderate-severe); * evaluate the possible association between different degrees of neutropenia and the presence of infections.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 16
Healthy Volunteers: f
View:

• presence of Duffy-null phenotype

Locations
Other Locations
Italy
Fondazione IRCCS Ca' Granda Ospedale Maggioe Policlinico
RECRUITING
Milan
Contact Information
Primary
Alessandra Cattaneo
alessandra.cattaneo@policlinico.mi.it
0255034252
Time Frame
Start Date: 2024-06-30
Estimated Completion Date: 2025-11-30
Participants
Target number of participants: 150
Treatments
Duffy null neutropenic subjects
Pediatric patients sent to our laboratory for anti-neutrophil antibodies evaluation in the suspicion of immune neutropenia
Related Therapeutic Areas
Sponsors
Leads: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

This content was sourced from clinicaltrials.gov