Optimal Timing of Euploid Day 6 Blastocyst (blastocyst Which Was Biopsied on Day 6 After Fertilization) Transfer in Frozen Hormonal Replacement Therapy Cycles: Day 6 or Day 7 of Progesterone Administration?

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure, Drug, Diagnostic test
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

The goal of this study is to compare the difference in clinical pregnancy, miscarriage and livebirth rate between day 6 euploid blastocyst transfer on the 6th and the 7th day of progesterone exposure in Hormonal Replacement Therapy (HRT) FET cycles. This prospective \& randomized study will only include euploid day 6 blastocysts. This will be the first prospective study of euploid day 6 blastocysts thereby excluding aneuploidy as a cause of miscarriage and implantation failure. The point of randomization will occur on the day of progesterone commencement.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 43
Healthy Volunteers: t
View:

• Women aged 18 years to 43 years.

• Having at least 1 euploid cryopreserved day 6 blastocyst of at least Grade BB quality.

• Endometrial trilaminar appearance on the day of progesterone start

Locations
Other Locations
United Arab Emirates
ART Fertility Clinics LLC
RECRUITING
Abu Dhabi
ART Fertility Clinics Dubai
RECRUITING
Dubai
Contact Information
Primary
Barbara Lawrenz, PhD
barbara.lawrenz@artfertilityclinics.com
+971 800 337845489
Backup
Jonalyn Edades, RN
jonalyn.edades@artfertilityclinics.com
+971 800 337845489
Time Frame
Start Date: 2023-09-22
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 316
Treatments
Other: Group A
Embryo transfer is scheduled on the 6th full day of progesterone administration, following the initial commencement of progesterone (120 hours)
Other: Group B
Embryo Transfer is scheduled on the 7th full day of progesterone administration, following the initial commencement of progesterone (144 hours)
Related Therapeutic Areas
Sponsors
Leads: ART Fertility Clinics LLC

This content was sourced from clinicaltrials.gov