Infertility Clinical Trials

Find Infertility Clinical Trials Near You

A Comparative Study of In Vitro Fertilization Outcomes Between PPOS and Antagonist Protocols in Women With Polycystic Ovary Syndrome

Status: Recruiting

Location: See location...

Intervention Type: Drug

Study Type: Interventional

Study Phase: Not Applicable

SUMMARY

This study aims to compare the outcomes of two ovarian stimulation protocols used in in vitro fertilization (IVF): the progestin-primed ovarian stimulation (PPOS) protocol and the GnRH antagonist protocol.

Eligibility

Participation Requirements

Sex: Female

Minimum Age: 18

Maximum Age: 40

Healthy Volunteers: f

View:

• Women aged 18-40 years

• Diagnosed with polycystic ovary syndrome (PCOS) according to the modified Rotterdam criteria (2004) (≥2 of 3: oligo/anovulation, hyperandrogenism, or polycystic ovarian morphology on ultrasound)

• Indicated for in vitro fertilization (IVF) due to PCOS alone or PCOS with other infertility factors (e.g., tubal factor, previous failed IUI)

• Eligible for controlled ovarian stimulation for IVF

• Husband/partner with normal sperm parameters or mild to moderate oligoasthenoteratozoospermia (OAT)

• Willing and able to provide written informed consent and comply with study procedures.

Locations

Other Locations

Viet Nam

Hanoi General Hospital

RECRUITING

Hanoi

Contact Information

Primary

Phuong Duy Nguyen, MD, MS

nguyenduyphuongncs44@gmail.com

+84 986656835

Time Frame

Start Date: 2026-01-20

Estimated Completion Date: 2028-06-30

Participants

Target number of participants: 400

Treatments

Experimental: PPOS Protocol

Participants receive ovarian stimulation using the progestin-primed ovarian stimulation (PPOS) protocol for in vitro fertilization.

Active_comparator: GnRH Antagonist Protocol

Participants receive ovarian stimulation using a GnRH antagonist protocol for in vitro fertilization.

Related Therapeutic Areas

Infertility

Polycystic Ovary Syndrome

Ovarian Cysts

Similar Clinical Trials

View All