GnRH for Luteal Support in IVF/ICSI/FET Cycles

Who is this study for? Patients with Infertility
What treatments are being studied? GnRH
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged endometrium, which subsequently must continue to develop to accommodate the growing and maturing embryo and then fetus. This process is normally regulated by hormonal interactions between the fetal, endometrial and luteal tissue. It has been found that after IVF additional support for the endometrium with progesterone improves implantation and subsequent live birth rates in IVF cycle . Recent data has shown that additional supplementation with a single administration of a GnRH agonist around the time the time of embryo transfer may further enhance these rates .

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:

• women undergoing IVF/ICSI or frozen embryo transfers (FET) that less than 40 years old.

Locations
United States
New Jersey
University Reproductive Associates
RECRUITING
Hasbrouck Heights
Contact Information
Primary
Peter G McGovern, MD
mcgovepg@gmail.com
201-288-6330
Time Frame
Start Date: 2015-11
Estimated Completion Date: 2026-07
Participants
Target number of participants: 350
Treatments
Experimental: GnRH agonist
Placebo_comparator: Placebo
Related Therapeutic Areas
Sponsors
Leads: University Reproductive Associates

This content was sourced from clinicaltrials.gov