Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

The goal of this study is to learn if a suprachoroidal triamcinolone injection can treat vision-threatening swelling in the center of the retina (macular edema) caused by non-infectious uveitis, especially in people who did not improve after a standard steroid injection around the eye (sub-Tenon injection). The main questions it aims to answer are: Does vision improve on the eye chart after the injection? Does the injection lower retinal swelling (reduction in thickness) within 3 months? Participants will: Have a pre-treatment check (vision test, slit-lamp exam, and a retinal scan called OCT). Receive one suprachoroidal triamcinolone injection under anesthetics drops in a sterile setting (operating room) with standard monitoring. Return for visits about 1 month and 3 months after treatment for repeat vision tests, and OCT scans. Contact the clinic if they notice pain, redness, new floaters, or worsening vision.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Non-infectious uveitis complicated with macular edema

• Uveitic macular edema of less than four months' duration

• Macular edema persisted despite lack of intra-ocular inflammation

• No response to posterior sub-Tenon triamcinolone acetonide injections

Locations
Other Locations
Iraq
Ibn Al-Haitham Eye Teaching Hospital
RECRUITING
Baghdad
Contact Information
Primary
Mohammed Suhail Al-Salam
mohammedsuhail@uomustansiriyah.edu.iq
+964 790 183 6367
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 20
Treatments
Experimental: Suprachoroidal Triamcinolone treatment arm
Sponsors
Leads: Baghdad college of medicine

This content was sourced from clinicaltrials.gov