Phase 2 5-Day Preoperative Radiation for Soft Tissue Sarcoma

Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The purpose of this study is to examine the safety and efficacy of an abbreviated course of preoperative radiation, given over five days, for patients with soft tissue sarcoma of the extremity, trunk or retroperitoneum. This is in contrast to standard preoperative radiation, which is given over 25 days.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Histologically confirmed soft tissue sarcoma of the extremity, trunk or retroperitoneum.

• Has been offered preoperative radiation and surgery as part of standard-of-care treatment

• Age ≥ 18

• KPS ≥ 70 or ECOG 0 to 2

• Life expectancy ≥ 6 months

• If a woman is of childbearing potential, a negative serum or urine pregnancy test must be documented.

• Ability to understand and the willingness to personally sign the written IRB approved informed consent document.

Locations
United States
California
Stanford University
RECRUITING
Palo Alto
Contact Information
Primary
Alyssa Yauger
ayauger@stanford.edu
650-498-5271
Backup
Camellia Djebroun
cdjebrou@stanford.edu
650-736-5564
Time Frame
Start Date: 2023-10-06
Estimated Completion Date: 2026-01
Participants
Target number of participants: 75
Treatments
Experimental: External beam radiotherapy
Patients will receive treatment with external beam radiotherapy at a total of 30 Gy delivered over five fractions delivered daily.
Related Therapeutic Areas
Sponsors
Leads: Stanford University

This content was sourced from clinicaltrials.gov