Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

SCANDARE is a prospective biobanking study on tumor (+/- nodes), plasma and blood samples at different time points in ovarian, triple negative breast, Head and Neck Cancer, advanced stage treatment-naïve cervical cancer and sarcoma (breast angiosarcoma and uterine sarcoma) cancers. This study will allowed to identify new molecular and/or immunological biomarkers associated with clinical and biological features of the tumors. All patients will receive standard treatment according to the stage of the diseases and usual procédures.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Tumor types :

‣ Newly diagnosed treatment-naïve ovarian cancer patients eligible for surgery or neoadjuvant chemotherapy

⁃ Newly diagnosed treatment-naïve triple-negative breast cancer patients eligible for surgery or neoadjuvant chemotherapy

⁃ Newly diagnosed treatment-naïve head and neck cancer patients eligible for surgery

⁃ Newly diagnosed treatment-naïve cervical cancer patients (1) stage Ia - IIa1 with nodal metastasis, postoperative positive margin or parametrial-vaginal involvement, and (2) stage ≥IIa2).

⁃ Newly diagnosed treatment-naïve sarcoma cancer patients (1) breast angiosarcoma or (2) uterine sarcoma eligible for surgery or systemic treatment

• Male or female patients ≥ 18 years of age

• Signed informed consent

Locations
Other Locations
France
Institut Bergonie
NOT_YET_RECRUITING
Bordeaux
Centre Oscar Lambret
RECRUITING
Lille
Centre Leon Berard
NOT_YET_RECRUITING
Lyon
Institut Curie
RECRUITING
Paris
Institut Curie Hopital Rene Huguenin
RECRUITING
Saint-cloud
Contact Information
Primary
Anne-Sophie PLISSONNIER
drci.promotion@curie.fr
01 47 11 23 78
Time Frame
Start Date: 2017-01-06
Estimated Completion Date: 2032-01-06
Participants
Target number of participants: 1050
Treatments
Experimental: Tumor and blood sampling
Patients will have a biopsy or a surgery and blood sampling at different time points.
Sponsors
Leads: Institut Curie

This content was sourced from clinicaltrials.gov