Treatment of BCR-ABL Negative ALL in Adults According to MRD and Genetics
Status: Recruiting
Location: See all (108) locations...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
After consolidation therapy adult patients (≥18 yr) with Ph-negative ALL will be treated with continuation chemotherapy or allogeneic hematopoietic stem cell transplantation (alloHSCT) according to both measurable residual disease (MRD) and results of genetic study performed at baseline.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• Patients 18-60 yr with de novo Ph-neg ALL
• Eastern Cooperative Oncology Group (ECOG) 0-2 (or \>2 if due to ALL)
• Informed consent
Locations
Other Locations
Spain
H. A Coruña
NOT_YET_RECRUITING
A Coruña
H Albacete
NOT_YET_RECRUITING
Albacete
H. General Univ. de Alicante
RECRUITING
Alicante
H. General Univ. de Alicante
NOT_YET_RECRUITING
Alicante
Hospital Nuestra Señora de Sonsoles
RECRUITING
Ávila
Ico-Hugtip
RECRUITING
Badalona
Clínica Teknon
NOT_YET_RECRUITING
Barcelona
H del Mar
NOT_YET_RECRUITING
Barcelona
H. Clínic de Barcelona
RECRUITING
Barcelona
H. del Mar
NOT_YET_RECRUITING
Barcelona
H. Sant Pau
RECRUITING
Barcelona
H. Vall d'Hebron
RECRUITING
Barcelona
H. Vall d'Hebron
NOT_YET_RECRUITING
Barcelona
ICO-Duran i Reynals
NOT_YET_RECRUITING
Bellvitge
H Basurto
NOT_YET_RECRUITING
Bilbao
Hu Basurto
RECRUITING
Bilbao
H. San Pedro de Alcántara
NOT_YET_RECRUITING
Cáceres
H. Jerez
NOT_YET_RECRUITING
Cadiz
H. Puerta del Mar
NOT_YET_RECRUITING
Cadiz
H. General de Castellón
NOT_YET_RECRUITING
Castelló
H. Reina Sofía
NOT_YET_RECRUITING
Córdoba
H. Fuenlabrada
NOT_YET_RECRUITING
Fuenlabrada
H Galdakao
NOT_YET_RECRUITING
Galdakao
H. Univ. De Getafe
NOT_YET_RECRUITING
Getafe
ICO-Dr.Josep Trueta
RECRUITING
Girona
H. Guadalajara
NOT_YET_RECRUITING
Guadalajara
H Juan Ramón Jiménez
NOT_YET_RECRUITING
Huelva
Complejo Hospitalario Ciudad de Jaén
RECRUITING
Jaén
H. Jerez de la Frontera
RECRUITING
Jerez De La Frontera
H. General Lanzarote
NOT_YET_RECRUITING
Lanzarote
H Dr. Negrín
RECRUITING
Las Palmas De Gran Canaria
Hospital Insular de Gran Canaria
NOT_YET_RECRUITING
Las Palmas De Gran Canaria
Hu Gran Canarias Dr Negrin
NOT_YET_RECRUITING
Las Palmas De Gran Canaria
H. Arnau De Vilanova
RECRUITING
Lleida
H. Lucus Augusti
NOT_YET_RECRUITING
Lugo
H. Lucus Augusti
NOT_YET_RECRUITING
Lugo
H. Lucus Augusti
NOT_YET_RECRUITING
Lugo
Fundación Jiménez Díaz
NOT_YET_RECRUITING
Madrid
H La Zarzuela
NOT_YET_RECRUITING
Madrid
H Puerta de Hierro
RECRUITING
Madrid
H Puerta de Hierro
NOT_YET_RECRUITING
Madrid
H. 12 de Octubre
NOT_YET_RECRUITING
Madrid
H. 12 de Octubre
NOT_YET_RECRUITING
Madrid
H. 12 de Octubre
NOT_YET_RECRUITING
Madrid
H. 12 de Octubre
NOT_YET_RECRUITING
Madrid
H. 12 de Octubre
NOT_YET_RECRUITING
Madrid
H. Clínico de Madrid
NOT_YET_RECRUITING
Madrid
H. Clínico de Madrid
NOT_YET_RECRUITING
Madrid
H. Gregorio Marañón
NOT_YET_RECRUITING
Madrid
H. Gregorio Marañón
NOT_YET_RECRUITING
Madrid
H. Infanta Sofía
NOT_YET_RECRUITING
Madrid
H. Madrid-Norte Sanchinarro
RECRUITING
Madrid
H. Ramón y Cajal
NOT_YET_RECRUITING
Madrid
H. Ramón y Cajal
RECRUITING
Madrid
H. Univ La Paz
NOT_YET_RECRUITING
Madrid
Hu Infanta Leonor
NOT_YET_RECRUITING
Madrid
Hu La Princesa
NOT_YET_RECRUITING
Madrid
H. Carlos Haya
NOT_YET_RECRUITING
Málaga
H. Clínico Univ. Virgen de la Victoria
RECRUITING
Málaga
H. Regional de Málaga
RECRUITING
Málaga
H. Morales Meseguer
NOT_YET_RECRUITING
Murcia
H. Virgen de la Arrixaca
NOT_YET_RECRUITING
Murcia
H. Virgen de la Arrixaca
NOT_YET_RECRUITING
Murcia
H. Virgen de la Arrixaca
NOT_YET_RECRUITING
Murcia
Complejo Hosp. Univ. de Orense
NOT_YET_RECRUITING
Ourense
Complejo Hosp. Univ. de Orense
NOT_YET_RECRUITING
Ourense
Complejo Hosp. Univ. de Orense
NOT_YET_RECRUITING
Ourense
Complejo Hosp. Univ. de Orense
NOT_YET_RECRUITING
Ourense
H. Central de Asturias
RECRUITING
Oviedo
H Río Carrión
NOT_YET_RECRUITING
Palencia
H. Son Espases
RECRUITING
Palma De Mallorca
H. Son Llàtzer
NOT_YET_RECRUITING
Palma De Mallorca
Complejo Hospitalario Navarra
RECRUITING
Pamplona
H. Clínico Univ. de Navarra
NOT_YET_RECRUITING
Pamplona
H. Virgen del Camino
NOT_YET_RECRUITING
Pamplona
Complejo Hospitalario Pontevedra - Hospital Montecelo
NOT_YET_RECRUITING
Pontevedra
H. Parc Taulí
NOT_YET_RECRUITING
Sabadell
H. Clínico Univ. de Salamanca
NOT_YET_RECRUITING
Salamanca
H. Clínico Univ. de Salamanca
NOT_YET_RECRUITING
Salamanca
H Donostia
NOT_YET_RECRUITING
San Sebastián
H Donostia
NOT_YET_RECRUITING
San Sebastián
H Donostia
NOT_YET_RECRUITING
San Sebastián
H Donostia
NOT_YET_RECRUITING
San Sebastián
H. Univ. de Canarias
NOT_YET_RECRUITING
Santa Cruz De Tenerife
H. Marqués de Valdecilla
NOT_YET_RECRUITING
Santander
H. Marqués de Valdecilla
NOT_YET_RECRUITING
Santander
Complejo Hosp. Univ. Santiago de Compostela
RECRUITING
Santiago De Compostela
Complejo Hosp. Univ. Santiago de Compostela
NOT_YET_RECRUITING
Santiago De Compostela
H. General de Segovia
NOT_YET_RECRUITING
Segovia
H. Universitario de Valme
NOT_YET_RECRUITING
Seville
H. Virgen del Rocío
RECRUITING
Seville
ICO-Joan XXIII
NOT_YET_RECRUITING
Tarragona
Mútua de Terrassa
NOT_YET_RECRUITING
Terrassa
H Torrejón
NOT_YET_RECRUITING
Torrejón De Ardoz
H. Verge de la Cinta
NOT_YET_RECRUITING
Tortosa
H. Arnau de Vilanova
NOT_YET_RECRUITING
Valencia
H. Clínico Univ. de Valencia
NOT_YET_RECRUITING
Valencia
H. Dr. Peset
NOT_YET_RECRUITING
Valencia
H. Dr. Peset
NOT_YET_RECRUITING
Valencia
H. General Univ. de Valencia
NOT_YET_RECRUITING
Valencia
H. la Fe
RECRUITING
Valencia
H. Clínico Universitario de Valladolid
NOT_YET_RECRUITING
Valladolid
H. Río Hortega
NOT_YET_RECRUITING
Valladolid
H. Xeral-Cíes Vigo
NOT_YET_RECRUITING
Vigo
H. Xeral-Cíes Vigo
NOT_YET_RECRUITING
Vigo
H. Virgen de la Concha
NOT_YET_RECRUITING
Zamora
H. Lozano Blesa
NOT_YET_RECRUITING
Zaragoza
H. Miguel Servet
NOT_YET_RECRUITING
Zaragoza
Contact Information
Primary
Josep Maria Ribera, Ph
jribera@iconcologia.net
934978987
Time Frame
Start Date: 2019-11-25
Estimated Completion Date: 2027-02
Participants
Target number of participants: 300
Treatments
Other: CHEMOTHERAPY
Pediatric-type of chemotherapy
Other: allogeneic HSCT
allogeneic HSCT
Related Therapeutic Areas
Sponsors
Leads: PETHEMA Foundation