Medical Events of Interest and Health-Related Quality of Life in Chronic Lymphocytic Leukemia Patients Initiating Treatment With Bruton's Tyrosine Kinase Inhibitors Acalabrutinib or Ibrutinib

Status: Completed
Location: See all (16) locations...
Study Type: Observational
SUMMARY

This is a multi-site observational study of medical events of interest (MEOI) and health-related quality of life (HRQoL) in chronic lymphocytic leukemia (CLL) patients initiating treatment with the Bruton's tyrosine kinase inhibitors (BTKi) acalabrutinib or ibrutinib in the United States (US)

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• ≥18 years old

• Physician-confirmed diagnosis of CLL or small lymphocytic lymphoma (SLL)

• BTKi naïve patients who initiate acalabrutinib or ibrutinib treatment alone or in combination with an anti-CD20 mAb within 7 days (before or after) study enrollment\*. Both treatment naïve and relapsed/refractory CLL patients will be included.

• Provides informed consent

• Adequate English reading skills

• Able to access and use a computer, tablet, or smartphone to complete PROs

Locations
United States
California
Research Site
Fountain Valley
Research Site
Redlands
Florida
Research Site
Boca Raton
Research Site
Fort Lauderdale
Research Site
St. Petersburg
Research Site
Tallahassee
Research Site
Tamarac
Research Site
Tampa
Georgia
Research Site
Savannah
Hawaii
Research Site
Honolulu
Mississippi
Research Site
Jackson
North Carolina
Research Site
Charlotte
New Jersey
Research Site
Berkeley Heights
New York
Research Site
Amherst
Pennsylvania
Research Site
Philadelphia
Research Site
York
Time Frame
Start Date: 2021-10-07
Completion Date: 2024-09-26
Participants
Target number of participants: 23
Treatments
Acalabrutinib
CLL patients initiating acalabrutinib alone or in combination with an anti-CD20 mAb
Ibrutinib
CLL patients receiving ibrutinib alone or in combination with an anti-CD20 mAb
Sponsors
Leads: AstraZeneca

This content was sourced from clinicaltrials.gov