• Patients who are able to understand and willing to sign the informed consent form (ICF).

• All patients should aged 14 to 75 years,no gender limitation.

• Patients with R/R AML, diagnosed in accordance with the 2021 edition of the CMA criteria

• Liver function: ALT and AST≤2.5 times the upper limit of normal ,bilirubin≤2 times the upper limit of normal;

• Renal function: creatinine ≤the upper limit of normal;

• Patients without any uncontrolled infections , without organ dysfunction or without severe mental illness;

• The score of Eastern Cooperative Oncology Group (ECOG) is 0-3,and the predicted survival ≥ 4 months.

• Patients without severe allergic constitution.