Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This randomised control clinical trial aims to investigate the effects of exercise training and diet on physical and functional fitness and immunological and metabolic changes in adults with chronic lymphocytic leukaemia. Investigators will randomise participants to either 12 weeks of supervised/semi-supervised exercise only, exercise + nutritional guidance, or no exercise.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Confirmed diagnosis of CLL (including small lymphocytic leukaemia) as per the International Workshop on CLL Guidelines.
• Male or female ≥ 18 years of age
• Able to walk on a treadmill or cycle on an ergometer
• Pass the Physical Activity Readiness Questionnaires (PAR-Q and PAR-Q+)
Locations
Other Locations
United Kingdom
University of Surrey
RECRUITING
Guildford
Contact Information
Primary
David Bartlett, PhD
d.bartlett@surrey.ac.uk
01483 683 245
Backup
Ellie Miles
e.e.miles@surrey.ac.uk
01483 688 559
Time Frame
Start Date: 2022-10-14
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 132
Treatments
Experimental: HIT Group
Exercise Only~* 3 sessions per week~* Aerobic + Resistance Exercises
Experimental: EXE+ Group
Exercise + Nutritional Guidance~* 3 sessions per week~* Aerobic + Resistance Exercises~* Dietary assessment at baseline and during with guidance on eating a healthy diet provided
No_intervention: Control Group
Control group will receive no exercise or nutritional guidance
Related Therapeutic Areas
Sponsors
Collaborators: American Society of Hematology
Leads: University of Surrey