Retinal Vessel Leakage in Cerebral Small Vessel Disease: a Sub-study of the Mild Stroke Study 3

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The goal of this observational study is to learn about leakage from retinal vessels in cerebral small vessel disease. The main questions it aims to answer are: * Does retinal vessel leakage occur in cerebral small vessel disease? * If it does, is the severity of retinal vessel leakage similar to the severity of cerebral small vessel disease generally? Participants will be tested using fluorescein angiography. This involves an intravenous injection of fluorescent dye, and is a very sensitive way to find leakage from retinal blood vessels. Participants will have already had brain scans and other examinations and tests to measure the severity of their cerebral small vessel disease. Our new retinal images will complement the information from these previous tests.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Membership in the Mild Stroke Study 3 cohort

• Contrast enhanced MRI within 12 months

• Clear optical media in both eyes, as assessed by study investigator

• Best corrected visual acuity (near vision) ≥N36

Locations
Other Locations
United Kingdom
NHS Lothian
RECRUITING
Edinburgh
Time Frame
Start Date: 2025-01-13
Estimated Completion Date: 2026-02-15
Participants
Target number of participants: 40
Sponsors
Leads: University of Edinburgh

This content was sourced from clinicaltrials.gov