National Cohort of Patients With Cowden's Disease and With a Constitutional Alteration of the PTEN Gene for the Prospective Assessment of the Risk of Cancer.
This is a multicentric, observational, retrospective and prospective study, aiming to estimate the risk of cancer occurrence in subjects carrying a PTEN mutation, based on the constitution of a national cohort.
• Male or female.
• Adult or child without age limit.
• Carrier of a constitutional or mosaic alteration of the PTEN gene established and/or confirmed by the Institut Bergonié's genetics laboratory, following a request for molecular diagnosis made between 1997 and 2027.
• Participant informed of his genetic diagnosis.
• Participant informed and not having expressed non-opposition to participate in the research.
• Participant affiliated to a French social security system in accordance with French law on research involving the human person.