Physical Rehabilitation of Long COVID by Heat Therapy

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical trial seeks to establish the tolerability and efficacy of at home lower-body heat therapy for improving functional capacity along with metabolic and vascular health in late-middle aged and older adults with PASC, also known as long COVID.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 90
Healthy Volunteers: f
View:

• Between the ages of 50 and 90 years

• Free from orthopedic limitations that would prohibit performing leg exercise

• BMI \< 40 kg/m2 and weigh \< 400lbs

• Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at least 2 months following SARS-CoV-2 infection

Locations
United States
Nebraska
University of Nebraska Omaha
RECRUITING
Omaha
Contact Information
Primary
Gwenael Layec, PhD
unovrl@unomaha.edu
402-554-3779
Time Frame
Start Date: 2025-09-17
Estimated Completion Date: 2029-08
Participants
Target number of participants: 99
Treatments
Experimental: Heat Therapy
At home heat therapy 5 times (40-55 min) per week for 8 weeks.
Sham_comparator: Control Therapy
Sham at home thermoneutral therapy 5 times (40-55 min) per week for 8 weeks.
Active_comparator: Walking Intervention Using Wearable Technology
+1,500-3000 steps per day 3-5 days a week for 8 weeks.
Related Therapeutic Areas
Sponsors
Leads: University of Nebraska
Collaborators: National Institute on Aging (NIA)

This content was sourced from clinicaltrials.gov