Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Systemic Lupus Erthymatosous (SLE) is achronic inflammatory multi system auto immue disease characterized by pathogenic auto anti bodies production against nuclear structures (Bolouri et al.,2022), SLE affecting mainly woemn of childbearing age and is chracterized by unpredictable flares and remissions , disease variety varied from mild episode disorder to arpidly progressive life -threatening illness.. LN is diagnosed by either the presence of proteinuria \>0.5g/day. active urinary sediment , or an unexplained rise in serum creatinine there fore , identifying new invasive biomarkers of LN severity and outcome is mandatory, Renal Arterial resistive index ( RRI) is anon invasive biomarker that has been studied as apotential indicator of disease activity in LN patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
View:

• Aged ≥18 years.

• SLE patients fulfilling the SLE International Collaborating Clinics (SLICC) classification criteria and matched controls.

• Patients cooperative and can answer questions.

• Patients who are able and willing to give written informed consent.

Locations
Other Locations
Egypt
Sohag university Hospital
RECRUITING
Sohag
Contact Information
Primary
Doaa R Abdelkarim, resident
doaa_rabea_post@med.sohag.edu.eg
01027673294
Backup
Esam M Abualfadl, professor
Time Frame
Start Date: 2024-10-01
Estimated Completion Date: 2025-10-30
Participants
Target number of participants: 55
Treatments
group SLE
Patients with SLE
group control
matched healthy subjects
Sponsors
Leads: Sohag University

This content was sourced from clinicaltrials.gov